Division of Gastroenterology, Department of Medicine, Kurume University School of Medicine, Kurume, Japan.
Dig Endosc. 2013 May;25 Suppl 2:90-3. doi: 10.1111/den.12066.
At present, the endoscopic approach is the most commonly adopted method for stenting in patients with unresectable malignant hilar biliary stricture. This procedure is important, as it determines the quality of life and prognosis of the patient. Regarding the quality of the stent material, self-expandable metallic stents (SEMS) are expected to show longer-term stent patency than plastic stents (PS), and their use as devices of first choice has been increasing. However, complications such as stent occlusion due to tumor ingrowth or biliary sludge formation occur at a considerably high frequency, necessitating reintervention in a considerable number of patients. In the case of dysfunction of an implanted PS, the stent is removed, and the lumen of the bile duct is cleaned, followed by placement of a new stent. In the event of dysfunction of a SEMS, cleaning of the lumen of the SEMS and placement of a second stent (PS is preferable) are carried out. Nevertheless, the results have not been entirely gratifying. Development of SEMS or PS suited to multidisciplinary treatment that would enable uncomplicated reintervention is anticipated.
目前,对于无法切除的恶性肝门胆管狭窄患者,内镜下支架置入术是最常用的方法。该操作非常重要,因为它决定了患者的生活质量和预后。就支架材料的质量而言,自膨式金属支架(SEMS)的支架通畅时间预计长于塑料支架(PS),并且作为首选器械的使用正在增加。然而,由于肿瘤生长或胆汁淤积形成等原因导致支架阻塞的并发症发生率相当高,需要对相当数量的患者进行再次介入治疗。在 PS 植入后发生功能障碍的情况下,需要取出支架,清洁胆管腔,然后再放置新的支架。如果 SEMS 发生功能障碍,则需要对 SEMS 的管腔进行清洁,并放置第二个支架(最好是 PS)。然而,结果并不完全令人满意。预计会开发出适合多学科治疗的 SEMS 或 PS,从而可以实现简单的再次介入治疗。