Murphy E, Gill D
Children's Hospital, Dublin.
Ir Med J. 1990 Mar;83(1):27-8.
Three boys with growth hormone deficiency were given biosynthetic human growth hormone, four units subcutaneously three times weekly, over two years. All three exceeded their expected growth velocities for bone age during the first year, but fared less well during the second year. Mean yearly growth velocities were: 3.2 cms before treatment, 7.1 cms after 12 months' treatment and 4.9 cms after a further 12 months. There were no adverse reactions.
三名生长激素缺乏的男孩接受了生物合成人生长激素治疗，每周皮下注射4单位，共两年，每周三次。在第一年，所有三名男孩的骨龄生长速度均超过预期，但在第二年情况不太理想。平均年生长速度分别为：治疗前3.2厘米，治疗12个月后7.1厘米，再过12个月后4.9厘米。未出现不良反应。
