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腹腔镜治疗十二指肠溃疡穿孔——一项多中心研究。

Laparoscopic treatment of perforated duodenal ulcer -- a multicenter study.

作者信息

Varcuş F, Lazăr F, Beuran M, Lica I, Turculeţ C, Nicolau Ea, Anghel R, Iordache F, Jinescu G, Murgu C, Vintilă D, Neacşu C, Bradea C, Georgescu St O, Popescu R, Sârbu V, Sabău D, Dumitra A, Sabău A, Antonescu N, Coman A, Picu A, Binţinţan V, Ciuce C

机构信息

"Victor Babeş" University of Medicine and Pharmacy, Surgical Department 2, Timişoara, Romania.

出版信息

Chirurgia (Bucur). 2013 Mar-Apr;108(2):172-6.

PMID:23618564
Abstract

AIM

The aim of this study is to evaluate the results of the laparoscopic treatment of perforated duodenal ulcer performed in 6 Romanian surgical centres with experience in the field of laparoscopic surgery.

MATERIAL AND METHOD

Between 1996 and 2005, 186 patients with perforated duodenal ulcer were operated on in the centers participating in this retrospective study, all patients being ASA I-II. Thirty-nine patients (20.0%) presented mild peritonitis, 120 (64.5%) medium peritonitis and 27 (15.5%) severe (20.0%) simple suture was performed, in 110 (59.1%) suture with epiplonoplasty, for 1 (0.5%) only epiplonoplasty and 1 (0.5%) underwent excision of the perforation and suture.

RESULTS

The operative time was between 30-120 minutes, with an average of 75 minutes. No death was noted. Average hospitalization time was 6 days, with periods varying between 3 and 18 days. Postoperative complications included: 5 patients (2,6%) presented infections of the abdominal walls, 1 patient (0.5%) duodenal fistula, 1 patient (0.5%) intra-abdominal abscess, 1 patient (0.5%) a superior digestive hemorrhage by "mirrored ulcer" and 1 patient (0.5%) duodenal stenosis 6 months after operation. The patients were administered 50% less analgesics, used 70% less dressings, 30% less antibiotics and had 60% less complications in comparison with those operated by the classical approach.

CONCLUSION

The laparoscopic approach of perforated duodenal ulcer constitutes the first choice for patients without important co-morbidities, allowing a quick recovery and a significant reduction in the consumption of analgesics, antibiotics and dressing materials.

摘要

目的

本研究旨在评估罗马尼亚6个在腹腔镜手术领域有经验的外科中心对穿孔性十二指肠溃疡进行腹腔镜治疗的结果。

材料与方法

1996年至2005年期间,参与这项回顾性研究的各中心对186例穿孔性十二指肠溃疡患者进行了手术,所有患者美国麻醉医师协会(ASA)分级为I-II级。39例患者(20.0%)表现为轻度腹膜炎,120例(64.5%)为中度腹膜炎,27例(15.5%)为重度腹膜炎。其中20.0%的患者进行了单纯缝合,110例(59.1%)进行了带网膜成形术的缝合,1例(0.5%)仅进行了网膜成形术,1例(0.5%)接受了穿孔切除及缝合。

结果

手术时间为30 - 120分钟,平均75分钟。无死亡病例。平均住院时间为6天,住院时间在3至18天之间。术后并发症包括:5例患者(2.6%)出现腹壁感染,1例患者(0.5%)出现十二指肠瘘,1例患者(0.5%)出现腹腔内脓肿,1例患者(0.5%)因“镜像溃疡”出现上消化道出血,1例患者(0.5%)术后6个月出现十二指肠狭窄。与采用传统手术方法的患者相比,这些患者使用的镇痛药减少了50%,敷料使用量减少了70%,抗生素使用量减少了30%,并发症减少了60%。

结论

对于无严重合并症的患者,穿孔性十二指肠溃疡的腹腔镜手术方法是首选,可使患者快速康复,并显著减少镇痛药、抗生素和敷料材料的消耗。

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