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非致密化心肌病与妊娠:令人担忧的共存却迎来良好结局。

Noncompaction cardiomyopathy and pregnancy: An alarming coexistence ending in a favourable outcome.

作者信息

Plastiras Sotiris C, Pamboucas Constantinos, Toumanidis Savvas

机构信息

Department of Clinical Therapeutics, University of Athens Medical School, "Alexandra" Hospital, Athens, Greece.

出版信息

Exp Clin Cardiol. 2012 Sep;17(3):136-8.

PMID:23620702
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3628427/
Abstract

Noncompaction of the left ventricular myocardium has gained increasing recognition over the past 25 years. This rare disease is caused by the arrest of myocardial morphogenesis. The classical triad of complications are heart failure, arrhythmias, including sudden cardiac death, and systemic embolic events. There is a paucity of data regarding women with left ventricular noncompaction cardiomyopathy and pregnancy outcome. The first report of an uneventful vaginal delivery without deterioration of left ventircular noncompaction cardiomyopathy is presented.

摘要

在过去25年里,左心室心肌致密化不全越来越受到关注。这种罕见疾病是由心肌形态发生停滞引起的。其经典的三联征并发症为心力衰竭、心律失常(包括心源性猝死)和全身性栓塞事件。关于患有左心室致密化不全心肌病的女性及其妊娠结局的数据很少。本文首次报道了一例阴道分娩顺利且左心室致密化不全心肌病未恶化的病例。

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本文引用的文献

1
Contrast echocardiography: contribution to diagnosis of left ventricular non-compaction cardiomyopathy.对比超声心动图:对左心室心肌致密化不全心肌病的诊断贡献。
Hellenic J Cardiol. 2011 May-Jun;52(3):265-72.
2
Systematic review of pregnancy in women with inherited cardiomyopathies.遗传性心肌病患者妊娠的系统评价。
Eur J Heart Fail. 2011 Jun;13(6):584-94. doi: 10.1093/eurjhf/hfr040. Epub 2011 Apr 11.
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Left ventricular non-compaction revisited: a distinct phenotype with genetic heterogeneity?左心室心肌致密化不全的再认识:一种具有遗传异质性的独特表型?
Eur Heart J. 2011 Jun;32(12):1446-56. doi: 10.1093/eurheartj/ehq508. Epub 2011 Jan 31.
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Speckle myocardial imaging modalities for early detection of myocardial impairment in isolated left ventricular non-compaction.斑点心肌成像技术在孤立性左心室心肌致密化不全心肌损伤早期检测中的应用。
Heart. 2010 Mar;96(6):440-7. doi: 10.1136/hrt.2009.182170. Epub 2009 Dec 4.
5
A case with noncompaction of the left ventricular myocardium detected by 64-slice multidetector computed tomography.一例经64层螺旋计算机断层扫描检测出的左心室心肌致密化不全病例。
J Thorac Imaging. 2009 Feb;24(1):38-40. doi: 10.1097/RTI.0b013e31818965f1.
6
Magnetic resonance in isolated noncompaction of the ventricular myocardium.磁共振在孤立性心室心肌致密化不全中的应用。
Int J Cardiol. 2010 Apr 30;140(3):367-9. doi: 10.1016/j.ijcard.2008.11.080. Epub 2008 Dec 25.
7
Left ventricular hypertrabeculation/noncompaction in a patient with peripartum cardiomyopathy.围生期心肌病患者的左心室心肌致密化不全/肥厚。
Int J Cardiol. 2010 Mar 4;139(2):e18-20. doi: 10.1016/j.ijcard.2008.08.025. Epub 2008 Sep 14.
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Left ventricular noncompaction mimicking peripartum cardiomyopathy.酷似围产期心肌病的左心室心肌致密化不全
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Successful outcome in a pregnant woman with isolated noncompaction of the left ventricular myocardium.一名孤立性左心室心肌致密化不全孕妇的成功治疗结果。
Intern Med. 2007;46(6):285-9. doi: 10.2169/internalmedicine.46.6186. Epub 2007 Mar 15.
10
Genetic analysis in patients with left ventricular noncompaction and evidence for genetic heterogeneity.左心室心肌致密化不全患者的基因分析及基因异质性证据
Mol Genet Metab. 2006 May;88(1):71-7. doi: 10.1016/j.ymgme.2005.11.009. Epub 2006 Jan 19.