通过 4-(1'-环己烯基)-5-碘-1,2,3-三唑与 4-苯基-1,2,4-三唑啉-3,5-二酮的环加成反应合成稠合多环化合物：离去碘的重要性。
Fused polycyclic compounds via cycloaddition of 4-(1'-cyclohexenyl)-5-iodo-1,2,3-triazoles with 4-phenyl-1,2,4-triazoline-3,5-dione: the importance of a sacrificial iodide leaving group.
机构信息
Department of Chemistry and Biochemistry, Florida State University, 95 Chieftan Way, Tallahassee, Florida 32306-4390, USA.
出版信息
J Org Chem. 2013 May 17;78(10):5038-44. doi: 10.1021/jo400271j. Epub 2013 Apr 26.
PMID:23621085
Abstract
4-(1'-Cyclohexenyl)-5-iodo-1,2,3-triazole and 4-phenyl-1,2,4-triazoline-3,5-dione undergo a formal Diels-Alder reaction, which following an S(N)2' solvolysis process to displace the iodo group affords a fused polycyclic compound.
摘要
4-(1'-环己烯基)-5-碘-1,2,3-三唑和 4-苯基-1,2,4-三唑啉-3,5-二酮发生 Diels-Alder 反应，随后通过 S(N)2' 溶剂解过程取代碘原子，得到稠合多环化合物。
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