Department of General, Endocrine and Digestive Surgery, Saint-Louis Hospital, APHP, Paris, France.
Dis Esophagus. 2014 Feb-Mar;27(2):122-7. doi: 10.1111/dote.12079. Epub 2013 Apr 26.
The objective of the study was to compare outcomes of emergency esophagogastrectomy (EGT) and total gastrectomy with immediate esophagojejunostomy (EJ) in patients with full-thickness caustic necrosis of the stomach and mild esophageal injuries. After caustic ingestion, optimal management of the esophageal remnant following removal of the necrotic stomach remains a matter of debate. Between 1987 and 2012, 26 patients (men 38%, median age 44 years) with isolated transmural gastric necrosis underwent EGT (n = 14) or EJ (n = 12). Early and long-term outcomes of both groups were compared. The groups were similar regarding age (P = 0.66), gender (0.24), and severity of esophageal involvement. Functional success was defined as nutritional autonomy after removal of the jejunostomy and tracheotomy tubes. Emergency morbidity (67% vs. 64%, P = 0.80), mortality (17% vs. 7%, P = 0.58), and reoperation rates (25% vs.14%, P = 0.63) were similar after EJ and EGT. One patient (8%) experienced EJ leakage. One patient in the EJ group and 13 patients in the EGT group underwent esophageal reconstruction (P < 0.0001). Aggregate in hospital length of stay was significantly longer in patients who underwent EGT (median 83 [33-201] vs. 36 [10-82] days, P = 0.001). Functional success after EJ and EGT was similar (90% vs.69%, P = 0.34). Immediate EJ can be safely performed after total gastrectomy for caustic injuries and reduces the need of further esophageal reconstruction.
研究目的是比较全层腐蚀性胃坏死合并轻度食管损伤患者行急诊胃切除术(EGT)和全胃切除加即刻食管空肠吻合术(EJ)的治疗结果。腐蚀性物质摄入后,对于坏死胃切除术后食管残端的最佳处理方法仍存在争议。1987 年至 2012 年间,26 例(男性占 38%,中位年龄 44 岁)孤立性全层胃坏死患者接受了 EGT(n = 14)或 EJ(n = 12)治疗。比较两组的早期和长期治疗结果。两组患者的年龄(P = 0.66)、性别(0.24)和食管受累严重程度相似。功能成功定义为经空肠造口和气管切开管拔出后实现营养自主。EJ 和 EGT 后急诊发病率(67% vs. 64%,P = 0.80)、死亡率(17% vs. 7%,P = 0.58)和再次手术率(25% vs. 14%,P = 0.63)相似。1 例(8%)EJ 患者发生吻合口漏。EJ 组中有 1 例患者和 EGT 组中有 13 例患者接受了食管重建(P < 0.0001)。EGT 组患者的住院总时长显著长于 EJ 组(中位数 83 [33-201] vs. 36 [10-82]天,P = 0.001)。EJ 和 EGT 后的功能成功率相似(90% vs. 69%,P = 0.34)。对于腐蚀性损伤,全胃切除术后即刻行 EJ 是安全的,可减少进一步的食管重建需求。