Lopes A, Frade I C, Teixeira L, Almeida M, Dias L, Henriques A C
Psychiatry and Health Psychology Unit, Hospital Geral de Santo António, Porto, Portugal.
Transplant Proc. 2013 Apr;45(3):1106-9. doi: 10.1016/j.transproceed.2013.02.100.
Quality of life (QOL) in donors before and after living kidney donor transplantation (LKDT) has been an important concern. Investigation of these issues in related recipients is not as common. Since 2002, a protocol of psychosocial evaluation for donors and recipients was included in the living kidney donation program. We sought to evaluate QOL in donors and recipients, before and after transplantation, and to compare the 2 groups.
Before and after transplantation, 35 recipients and 45 donors completed a Sociodemographic Questionnaire and Short-Form 36 Health Survey Questionnaire (SF-36). The Wilcoxon test, Mann-Whitney test, and logistic regression were applied.
Before transplantation, recipients had lower QOL values than donors for all dimensions (P < .05), with the exception of Mental Health. After transplantation, they had higher values (P < .05) for every dimension on the SF-36. Among donors, there were no significant changes. Physical function and social function were considered poorer by donors versus recipients (P < .05).
In this LKDT program, more females were donors and fewer were recipients. Most of donors were siblings. All donors were related (the Portuguese law pertaining to unrelated donation was enacted in 2007). QOL was significantly poorer among recipients before surgery. After surgery, QOL significantly improved in recipients and was not poorer in donors. LKDT improved recipients' lives and did not affect donors' negatively.
活体肾移植(LKDT)前后供体的生活质量(QOL)一直是一个重要关注点。对相关受者这些问题的调查并不常见。自2002年以来,活体肾捐赠项目纳入了供体和受者的社会心理评估方案。我们试图评估移植前后供体和受者的生活质量,并比较两组情况。
移植前后,35名受者和45名供体完成了一份社会人口学问卷和简短健康调查问卷(SF - 36)。应用了Wilcoxon检验、Mann - Whitney检验和逻辑回归分析。
移植前,除心理健康维度外,受者在所有维度的生活质量值均低于供体(P <.05)。移植后,他们在SF - 36的每个维度上的值都更高(P <.05)。在供体中,没有显著变化。供体认为身体功能和社会功能比受者差(P <.05)。
在这个活体肾移植项目中,女性供体较多,受者较少。大多数供体是兄弟姐妹。所有供体均有亲属关系(葡萄牙关于非亲属捐赠的法律于2007年颁布)。术前受者的生活质量明显较差。术后,受者的生活质量显著改善,供体的生活质量也不差。活体肾移植改善了受者的生活,且未对供体产生负面影响。