Division of Cardiac Surgery, San Giovanni Battista Hospital "Molinette," University of Turin, Turin, Italy; Department of Surgery, Dipartimento di Scienze Chirurgiche, Rianimatorie-Riabilitative e dei Trapianti d'Organo, Fondazione IRCCS "San Matteo" Hospital, University of Pavia, Pavia, Italy.
Division of Cardiac Surgery, San Giovanni Battista Hospital "Molinette," University of Turin, Turin, Italy.
J Thorac Cardiovasc Surg. 2014 Mar;147(3):996-1001. doi: 10.1016/j.jtcvs.2013.03.018. Epub 2013 Apr 25.
Reports of minimally invasive tricuspid valve operations are rare, and results are often contradictory. This study analyzes our 5-year experience with minimally invasive tricuspid valve operations in high-risk patients.
Between November 2005 and December 2011, tricuspid valve surgery using a nonsternotomy minimally invasive technique was performed in 64 patients (19 male, 45 female; mean age, 63.2 ± 12.8 years). Mean preoperative European System for Cardiac Operative Risk Evaluation was 7.3 ± 2.9, and predicted mortality was 11.6% ± 11.7%. Tricuspid valve regurgitation cause was functional in 36 patients (56.2%), endocarditis in 2 patients (3.1%), and rheumatic in 24 patients (37.5%). Two patients (3.1%) showed prosthesis dysfunction. Forty patients (62.5%) had undergone previous cardiac surgery.
Tricuspid valve repair was performed in 35 patients (54.7%). Tricuspid valve replacement with bioprosthesis was performed in 27 patients (42.2%), and the remaining 2 patients (3.1%) underwent bioprosthetic replacement. Concomitant procedures (48) included mitral valve surgery (42 patients), atrial septal defect closure (5 patients), and myxoma exeresis (1 patient). Conversion to sternotomy occurred in 1 patient (1.6%). Overall hospital mortality was 7.9%. Stroke occurred in 1 patient (1.6%), and 5 patients underwent reoperation for bleeding (7.8%). Mean follow-up time was 21 ± 16 months (range, 1-59 months) and 100% completed. Cumulative Kaplan-Meier estimated 5-year survival was 81.3%, and 5-year freedom from reoperation was 100%.
The heart-port-based minimally invasive approach seems to be safe, feasible, and reproducible in case of tricuspid valve operations. It ensures low perioperative morbidity, moderate to low rates of tricuspid regurgitation recurrence, and low late mortality. It also seems to have an added value in case of reoperative procedures.
微创三尖瓣手术的报告很少见,结果往往相互矛盾。本研究分析了我们在高危患者中进行微创三尖瓣手术的 5 年经验。
2005 年 11 月至 2011 年 12 月,采用非胸骨切开微创技术对 64 例患者(19 例男性,45 例女性;平均年龄 63.2±12.8 岁)进行了三尖瓣手术。术前欧洲心脏手术风险评估系统平均为 7.3±2.9,预测死亡率为 11.6%±11.7%。三尖瓣反流的病因在 36 例患者(56.2%)中为功能性,在 2 例患者(3.1%)中为心内膜炎,在 24 例患者(37.5%)中为风湿性。有 2 例患者(3.1%)出现假体功能障碍。40 例患者(62.5%)曾接受过心脏手术。
35 例患者(54.7%)行三尖瓣修复术。27 例患者(42.2%)行生物瓣置换术,其余 2 例患者(3.1%)行生物瓣置换术。同时进行的手术(48 例)包括二尖瓣手术(42 例)、房间隔缺损修补术(5 例)和黏液瘤切除术(1 例)。1 例患者(1.6%)转为胸骨切开术。全组住院死亡率为 7.9%。1 例患者(1.6%)发生中风,5 例患者因出血再次手术(7.8%)。平均随访时间为 21±16 个月(1-59 个月),100%完成。累积 Kaplan-Meier 估计 5 年生存率为 81.3%,5 年无再次手术生存率为 100%。
基于心端口的微创方法在三尖瓣手术中似乎是安全、可行和可重复的。它确保了围手术期发病率低、中低程度的三尖瓣反流复发率和低晚期死亡率。它在再次手术中似乎也具有附加价值。