Dipartimento di Patologia Animale, Università degli Studi di Torino, Via L. da Vinci 44, 10095 Grugliasco, TO, Italy.
Res Vet Sci. 2013 Oct;95(2):569-71. doi: 10.1016/j.rvsc.2013.03.024. Epub 2013 Apr 24.
A wild Beech Marten (Martes foina), was referred for necropsy to the Department of Animal Pathology of the University of Turin (Italy). At gross examination, whitish and firm masses, 10-mm in diameter, were found on the heart and in the kidney. Spleen showed lighter color and greater consistency, and the cut surface of the liver appeared scattered with whitish-yellow coalescing foci homogeneously distributed. Amyloid deposits were present in the perivascular and intercellular spaces of the visceral organs, such as the heart, liver, and kidneys. Amyloid stained positively with Congo red with and without 5% potassium permanganate pretreatment and showed green birefringence observable under polarized light. A diagnosis of systemic AL amyloidosis was made. This is the first description of systemic AL amyloidosis in a wild Stone Marten.
一只野生貉（Martes foina）被送到都灵大学（意大利）动物病理学系进行剖检。在大体检查时，在心脏和肾脏上发现了直径 10 毫米的灰白色且坚硬的肿块。脾脏颜色较浅，质地较硬，肝脏切面可见散布着灰白色、黄色融合的病灶，呈均匀分布。在心脏、肝脏和肾脏等内脏器官的血管周围和细胞间空间存在淀粉样物质沉积。刚果红染色阳性，未经和经 5%高锰酸钾预处理后均呈阳性，在偏振光下观察到绿色双折射。诊断为系统性 AL 淀粉样变性。这是首例野生石貂发生系统性 AL 淀粉样变性的描述。
