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糖尿病与血管疾病:病理生理学、临床后果和医学治疗:第二部分。

Diabetes and vascular disease: pathophysiology, clinical consequences, and medical therapy: part II.

机构信息

Brigham and Women's Hospital and Harvard Medical School, 75 Francis Street, Boston, MA 02115, USA.

出版信息

Eur Heart J. 2013 Aug;34(31):2444-52. doi: 10.1093/eurheartj/eht142. Epub 2013 Apr 26.

Abstract

In part II of this review, we describe the epidemiology and clinical consequences of vascular disease in patients with diabetes, and discuss the efficacy of risk factor modification and antiplatelet treatment. Specifically, evidence-based cardiovascular therapies are discussed through novel clinical insights on management of hyperglycaemia, hypertension, dyslipidaemia as well as platelet dysfunction. Recent trends in the incidence and outcomes of vascular disease in diabetes suggest that timely and effective implementation of therapies is making a favourable impact.

摘要

在本综述的第二部分,我们描述了糖尿病患者血管疾病的流行病学和临床后果,并讨论了危险因素改变和抗血小板治疗的疗效。具体而言,通过对高血糖、高血压、血脂异常以及血小板功能障碍管理的新临床见解,讨论了基于证据的心血管治疗方法。糖尿病血管疾病发病率和结局的最新趋势表明,及时有效地实施治疗正在产生有利影响。

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