Yang Jin-Chuan, Tong Jing, Zhang Chuan-Ling, Wang Bao-An, Ding Ren, Du Yang-Guang, Yan Jia-Lu, Wu Wei-Wei, Liu Ting-Jun, Zhang Lei, Tang Liu-Ying
Xuzhou Center for Disease Control and Prevention, Jiangsu 221006, China.
Zhonghua Shi Yan He Lin Chuang Bing Du Xue Za Zhi. 2012 Dec;26(6):412-4.
To investigate the prevalence and subtypes of influenza viruses in Xuzhou city from 2005 to 2011 and to provide the scientific supports for influenza prevention and control in this religion.
The throat swab samples were collected from the influenza-like cases from national influenza like illness sentinel hospital in Xuzhou. The samples were used for influenza virus isolation and identification, sent on the national flu center to confirm according to the "national influenza surveillance program" and "influenza virus and experimental technology".
From Oct. 2005 to Dec. 2011, a total of 9561 swab specimens were collected in which 1152 strains were identified for influenza viruses with total isolated rate of 12.0%. Among these strains, 708 strains were A1 (H1N1) subtype (14.2%), 466 strains were A3 (H3N2) subtype (40.5%), 78 strains were new H1N1 subtype (6.8%), 362 strains were BV (Victoia) subtype (31.4%) and 82 strains were BY (Yamagate) subtype (7.1%). The top detection rate (25.9%) arose in 2007, secondary detection rate (17.4%) occurred at 2009 and the lowest one (2.3%) appeared in 2011. From the winter of 2005 to the spring of 2006 A1 (H1N1) subtype had appeared as predominant strains but in the winter of 2006 the predominant strains were BV subtype. It changed to A3 subtype in 2007 to 2009 and the other three dominant strains were A1, BV and BY in 2008. In the winter of 2009, both A3 (H3N2) and new H1N1 subtype were predominant strains. BV subtype was predominant strains in 2010 to 2011. The prevalence of A3 subtype appeared in all the year while prevalence of BV only arose in the spring and winter. So the detection rate was high in January (34.4%) but low in August (2.2%). The influenza population is correlated with age, the highest detection rate arose in 5-age group and the lowest detection rate appeared in 25-age group.
Influenza subtype A1, A3, New H1N1 are all appeared as predominant strains in Xuzhou city from 2005 to 2010. Besides, the prevalence of BV subtype is stronger in recently.
调查2005年至2011年徐州市流感病毒的流行情况及亚型，为该地区流感防控提供科学依据。
从徐州市国家级流感样病例监测哨点医院采集流感样病例的咽拭子样本，按照《全国流感监测方案》和《流感病毒及实验技术》进行流感病毒分离鉴定，并送国家流感中心确认。
2005年10月至2011年12月，共采集9561份咽拭子标本，其中1152株流感病毒被鉴定出来，总分离率为12.0%。其中，708株为A1（H1N1）亚型（14.2%），466株为A3（H3N2）亚型（40.5%），78株为新型H1N1亚型（6.8%），362株为BV（维多利亚）亚型（31.4%），82株为BY（山形）亚型（7.1%）。检出率最高的年份为2007年（25.9%），其次为2009年（17.4%），最低为2011年（2.3%）。2005年冬到2006年春，A1（H1N1）亚型为优势毒株，2006年冬优势毒株变为BV亚型，2007年至2009年变为A3亚型，2008年其他三种优势毒株为A1、BV和BY。2009年冬，A3（H3N2）和新型H1N1亚型均为优势毒株。2010年至2011年优势毒株为BV亚型。A3亚型全年均有流行，BV亚型仅在春秋季流行较高，1月份检出率最高（34.4%），8月份最低（2.2%）。流感人群与年龄相关，5岁组检出率最高，25岁组检出率最低。
2005年至2010年，A1、A3、新型H1N1亚型均为徐州市的优势毒株，且近期BV亚型流行较强。
