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改良 Cabrol 手术的中期经验:用于复杂主动脉根部替换术安全且持久。

Midterm experience with modified Cabrol procedure: safe and durable for complex aortic root replacement.

机构信息

Aortic Institute, Yale University, New Haven, Conn; Department of Surgical Diseases 2, Kazan State Medical University, Kazan, Russia.

Xavier University of Louisiana, New Orleans, La.

出版信息

J Thorac Cardiovasc Surg. 2014 Apr;147(4):1233-9. doi: 10.1016/j.jtcvs.2013.03.027. Epub 2013 Apr 26.

Abstract

OBJECTIVE

To evaluate the early and late outcomes of the modified Cabrol technique as a method of coronary reimplantation during complex composite graft replacement of the ascending aorta.

METHODS

Between 1995 and 2012, 348 patients (mean age, 56 ± 14 years; 283 males and 65 females) underwent composite graft replacement of the ascending aorta, 40 of whom (mean age, 60 ± 12 years; 35 males and 5 females) had one or both coronary ostia reimplanted using a modified Cabrol technique with an 8- to 10-mm Dacron interposition graft. The mean clinical and radiologic (computed tomographic scan) postoperative follow-up was 39 months (range, 1-171 months), via our aortic database, patient interviews, and Social Security Death Index.

RESULTS

Cabrol reimplantation was necessitated by reoperations with anatomically fixed coronary ostia (n = 16, 40%), severely displaced coronary arteries (n = 15, 37.5%), button calcification (n = 4, 10%), coronary anomalies (n = 3, 7.5%), and coronary aneurysm (n = 2, 5%). Of the operations, 20% (8 patients) were urgent interventions. Early mortality was 3 (7.5%) of 40, none related to the Dacron interposition graft. Total late mortality was 16.2%, also not related to the coronary graft. Actuarial survivals were 0.88 ± 0.05, 0.79 ± 0.07, and 0.73 ± 0.08 at 1, 3, and 6 years, respectively. Radiologic follow-up was available for 31 (83.8%) of the surviving patients and revealed that the interposition graft was widely patent in all.

CONCLUSIONS

The modified Cabrol technique using a Dacron interposition graft showed good survival rates and excellent durability over time, confirmed radiographically. These data confirm that it is appropriate to use the Cabrol technique when technical complexity prevents bringing coronary buttons to the main aortic graft.

摘要

目的

评估改良的 Cabrol 技术作为一种在复杂复合移植物替换升主动脉期间进行冠状动脉再植入的方法的早期和晚期结果。

方法

1995 年至 2012 年间,348 例患者(平均年龄 56±14 岁;283 名男性和 65 名女性)接受了升主动脉复合移植物置换,其中 40 例(平均年龄 60±12 岁;35 名男性和 5 名女性)使用改良的 Cabrol 技术进行了单支或双支冠状动脉再植入,使用 8-10mm 涤纶间置移植物。通过我们的主动脉数据库、患者访谈和社会保障死亡指数,平均临床和放射学(计算机断层扫描)术后随访 39 个月(范围 1-171 个月)。

结果

Cabrol 再植入是由于解剖固定的冠状动脉口(n=16,40%)、严重移位的冠状动脉(n=15,37.5%)、纽扣钙化(n=4,10%)、冠状动脉异常(n=3,7.5%)和冠状动脉瘤(n=2,5%)而需要进行的再手术。手术中,20%(8 例)为紧急干预。早期死亡率为 40 例中的 3 例(7.5%),均与涤纶间置移植物无关。总晚期死亡率为 16.2%,也与冠状动脉移植物无关。术后 1、3、6 年的生存率分别为 0.88±0.05、0.79±0.07 和 0.73±0.08。31 例(83.8%)存活患者的放射学随访显示,间置移植物在所有患者中均广泛通畅。

结论

使用涤纶间置移植物的改良 Cabrol 技术显示出良好的生存率和随时间推移的良好耐久性,这在影像学上得到了证实。这些数据证实,当技术复杂性阻止将冠状动脉纽扣带到主主动脉移植物时,使用 Cabrol 技术是合适的。

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