Center for Cardiovascular Research, Division of Cardiology and at the Department of Medicine, Washington University School of Medicine, 660 South Euclid Avenue, Campus Box 8086, St Louis, Missouri 63110, USA.
Nat Rev Drug Discov. 2013 May;12(5):327-8. doi: 10.1038/nrd4005.
Although investigators are encouraged to translate their laboratory research to impact the care of patients, there is an unappreciated downside to participating in “T1 translation” from the standpoint of the investigator if their translational efforts do not yield positive results in pivotal clinical trials.
尽管鼓励研究人员将实验室研究转化为对患者护理的影响,但如果他们的转化努力在关键临床试验中没有产生积极结果,从研究人员的角度来看,参与“T1 转化”存在未被认识到的缺点。