Klemeyer-Smith A, Thune P O, Bjørneboe G E
Hudavdelingen Ullevål sykehus, Oslo.
Tidsskr Nor Laegeforen. 1990 May 30;110(14):1817-9.
Psoriasis is an inflammatory condition of the skin which affects about 2% of the population. Several new treatment modalities have been introduced in recent years. This review considers the mode of action of various forms of treatment, side effects and therapeutic results that have been observed. Etretinate is a synthetic vitamin A analogue. It works alone, or even better in combination with psoralen plus ultraviolet light A (PUVA) or ultraviolet light B (UVB). Cyclosporin is still on trial, but seems to be effective in small doses and can be considered as an alternative in cases of psoriasis that are resistant to other therapies. The interest in dietary measures for psoriasis has been revived after some studies have suggested that dietary supplements of fish oil, a low-fat diet, can improve the condition. Now that n-3-fatty acids are available in capsule form it should be possible to prescribe a diet that is rich enough in fish oils.
银屑病是一种皮肤炎症性疾病，约影响2%的人口。近年来已引入了几种新的治疗方式。本综述考虑了各种治疗形式的作用方式、副作用及已观察到的治疗效果。依曲替酯是一种合成的维生素A类似物。它可单独使用，与补骨脂素加紫外线A（PUVA）或紫外线B（UVB）联合使用效果更佳。环孢素仍在试验中，但小剂量时似乎有效，可作为对其他疗法耐药的银屑病病例的一种替代治疗。一些研究表明，补充鱼油的低脂饮食可改善病情，之后人们对银屑病的饮食措施又重新产生了兴趣。既然现在有胶囊形式的n-3脂肪酸，那么就应该能够开出富含鱼油的饮食处方。
