Department of Emergency and Organ Transplant (D.E.T.O.), Section of Veterinary Clinics and Animal Production, University of Bari Aldo Moro, 70010 Valenzano, Bari, Italy.
Mar Pollut Bull. 2013 Jun 15;71(1-2):23-8. doi: 10.1016/j.marpolbul.2013.03.041. Epub 2013 Apr 28.
The Atlantic bluefin tuna Thunnus thynnus (ABFT) is intensely fished in the Mediterranean Sea to supply a prosperous capture-based mariculture industry. Liver apoptotic structures and tumor necrosis factor (TNF) gene expression were determined in: wild ABFT caught in the eastern Atlantic; juvenile ABFT reared in the central Adriatic Sea; juvenile ABFT reared in the northern Adriatic Sea; adult ABFT reared in the western Mediterranean. The highest density of liver apoptotic structures was found in the juveniles from the northern Adriatic. Two partial TNF cDNAs (TNF1 and TNF2) were cloned and sequenced. TNF1 gene expression was higher in juveniles than in adults. The highest expression of TNF2 was found in the juveniles from the northern Adriatic. These findings might be related to the juvenile exposure to environmental pollutants.
大西洋金枪鱼 Thunnus thynnus（ABFT）在地中海被大量捕捞，以供应繁荣的基于捕捞的海水养殖产业。本研究在以下几个方面对其进行了研究：在东大西洋捕捞的野生 ABFT；在亚得里亚海中部养殖的幼年 ABFT；在亚得里亚海北部养殖的幼年 ABFT；在西地中海养殖的成年 ABFT。在亚得里亚海北部养殖的幼年 ABFT 肝脏凋亡结构和肿瘤坏死因子（TNF）基因表达的密度最高。克隆并测序了两个 TNF 部分 cDNA（TNF1 和 TNF2）。TNF1 基因在幼鱼中的表达高于成年鱼。TNF2 的表达在亚得里亚海北部的幼鱼中最高。这些发现可能与幼鱼接触环境污染物有关。
