Texas Oncology Surgical Specialists, Baylor Sammons Cancer Center, 3410 Worth Street, Suite 160, Dallas, TX 75246, USA.
Surg Clin North Am. 2013 Jun;93(3):663-74. doi: 10.1016/j.suc.2013.02.005. Epub 2013 Mar 27.
Historically, borderline resectable (BLR) pancreatic cancer has had many definitions, which has made interpretation of treatment data and outcomes difficult. Advances in imaging, surgical technique, and the potential benefit of neoadjuvant therapy have emphasized the need for uniform classification. Despite recent efforts to provide a clearer definition, prospective randomized trials are lacking in the literature. This article reviews current definitions, treatment sequences, outcomes, and prognostic factors associated with BLR pancreatic cancer. Further clarification and consensus on the definition of BLR pancreatic cancer will allow for further data collection and cooperation in future efforts to make progress and standardize treatment.
从历史上看，交界可切除（BLR）胰腺癌有许多定义，这使得治疗数据和结果的解释变得困难。影像学、手术技术的进步以及新辅助治疗的潜在获益强调了统一分类的必要性。尽管最近在努力提供更明确的定义，但文献中仍然缺乏前瞻性随机试验。本文综述了 BLR 胰腺癌的当前定义、治疗顺序、结果和预后因素。进一步澄清和达成共识交界可切除（BLR）胰腺癌的定义将有助于进一步收集数据，并在未来的努力中合作，以取得进展和标准化治疗。
