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[卡尔曼滤波分光光度法同时测定复方利血平片中的6种成分]

[Simultaneous determination of 6 components contained in compound reserpine tablets by Kalman filtering spectrophotometry].

作者信息

Xu J P, Xiang B R, An D K

机构信息

Department of Pharmaceutical Analysis, China Pharmaceutical University, Nanjing.

出版信息

Yao Xue Xue Bao. 1990;25(1):77-80.

PMID:2363362
Abstract

Kalman filtering spectrophotometry was investigated to assay the contents of vitamin B1, vitamin B6, chlordiazepoxide, dihydralazine sulfate, promethazine hydrochloride and hydrochlorothiazide in compound reserpine tablets consisting of 10 components. Absorption proportionality constant for each component was obtained by the application of non-negative least square method. The average recoveries for each were 97-103% with CV% less than or equal to 6.9 except vitamin B1 (n = 11).

摘要

采用卡尔曼滤波分光光度法测定了由10种成分组成的复方利血平片中维生素B1、维生素B6、氯氮卓、硫酸双肼屈嗪、盐酸异丙嗪和氢氯噻嗪的含量。通过非负最小二乘法获得了各成分的吸收比例常数。除维生素B1外(n = 11),各成分的平均回收率为97 - 103%,变异系数小于或等于6.9%。

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