Chawla Rajeshwar, Ramalingam Karthikeyan, Sarkar Amitabha, Muddiah Savita
Department of Oral and Maxillofacial Pathology and Microbiology, JCD Dental College, Sirsa, Haryana, India.
J Nat Sci Biol Med. 2013 Jan;4(1):171-6. doi: 10.4103/0976-9668.107285.
Ameloblastoma is a rare, benign tumor of odontogenic epithelium, but with an aggressive clinical behavior.
The present study aims to assess the ultramicroscopic features of the epithelial and connective tissue components of ameloblastoma.
Six cases of ameloblastoma were subjected to electron microscopy. They included three cases of follicular type and three cases of plexiform type.
The study reveals that the ameloblastoma contains the full complement of cells normally found during odontogenesis. However, these cells resemble the enamel organ in an undifferentiated stage.
Ultramicroscopy revealed the presence of different cell types among follicular type. The morphology of plexiform variants and correlation with odontogenesis could be elicited. The electron microscopic differences between follicular and plexiform types could help us in better understanding its pathogenesis.
成釉细胞瘤是一种罕见的牙源性上皮良性肿瘤,但具有侵袭性临床行为。
本研究旨在评估成釉细胞瘤上皮和结缔组织成分的超微结构特征。
对6例成釉细胞瘤进行电子显微镜检查。其中包括3例滤泡型和3例丛状型。
研究表明,成釉细胞瘤包含牙胚发生过程中正常存在的全部细胞成分。然而,这些细胞类似于未分化阶段的釉器。
超微显微镜检查显示滤泡型中有不同细胞类型存在。可以明确丛状型变体的形态及其与牙胚发生的相关性。滤泡型和丛状型之间的电子显微镜差异有助于我们更好地理解其发病机制。