一名α地中海贫血患者的胸内肿瘤表现为髓外造血。
Extramedullary haematopoiesis presented as intrathoracic tumour in a patient with alpha-thalassaemia.
作者信息
Bobylev Dmitry, Zhang Ruoyu, Haverich Axel, Krueger Marcus
机构信息
Department of Cardiothoracic, Transplantation, and Vascular Surgery, Hannover Medical School, Carl-Neuberg-Str, 1, 30625, Hannover, Germany.
出版信息
J Cardiothorac Surg. 2013 May 1;8:120. doi: 10.1186/1749-8090-8-120.
Abstract
The authors report a case of extramedullary haematopoiesis (EMH) presenting as an intrathoracic tumour in a patient with alpha-thalassaemia. CT scan and MRI of the chest were obtained and followed by tumour excision. Compared to beta-thalassaemia, only two cases of EMH in patients with alpha-thalassaemia have been described in the literature. A possible reason for this disparity is discussed.
摘要
作者报告了一例α地中海贫血患者出现的髓外造血（EMH），表现为胸腔内肿瘤。对胸部进行了CT扫描和MRI检查，随后进行了肿瘤切除。与β地中海贫血相比，文献中仅描述了两例α地中海贫血患者的EMH病例。本文讨论了造成这种差异的一个可能原因。
相似文献
1
Extramedullary haematopoiesis presented as intrathoracic tumour in a patient with alpha-thalassaemia.一名α地中海贫血患者的胸内肿瘤表现为髓外造血。
J Cardiothorac Surg. 2013 May 1;8:120. doi: 10.1186/1749-8090-8-120.
2
Intrathoracic extramedullary hematopoietic tumor in hemoglobin H disease.血红蛋白H病中的胸内髓外造血肿瘤。
Am J Hematol. 1992 Dec;41(4):285-8. doi: 10.1002/ajh.2830410412.
3
Intrathoracic extramedullary haematopoiesis complicated by massive haemothorax in alpha-thalassaemia.α地中海贫血合并大量血胸的胸腔内髓外造血
Thorax. 1999 May;54(5):466-8. doi: 10.1136/thx.54.5.466.
4
Extramedullary haematopoiesis in patients with transfusion dependent β-thalassaemia (TDT): a systematic review.输血依赖型β地中海贫血（TDT）患者的骨髓外造血：系统评价。
Ann Med. 2022 Dec;54(1):764-774. doi: 10.1080/07853890.2022.2048065.
5
A rare case of adrenal extramedullary haematopoiesis in a Cypriot woman with β-thalassaemia.一名塞浦路斯β-地中海贫血妇女罕见的肾上腺髓外造血病例。
Ann R Coll Surg Engl. 2024 Apr;106(4):329-337. doi: 10.1308/rcsann.2021.0298. Epub 2022 Jan 4.
6
A patient with pancreatitis, anaemia and an intrathoracic tumour. Diagnosis: tumour-simulating asymptomatic intrathoracic extramedullary haematopoiesis (EMH) in a patient with hereditary spherocytosis.一名患有胰腺炎、贫血和胸内肿瘤的患者。诊断：遗传性球形红细胞增多症患者中出现模拟肿瘤的无症状胸内髓外造血（EMH）。
Eur Respir J. 2006 Apr;27(4):856-9. doi: 10.1183/09031936.06.00105905.
7
Pulmonary emboli and extramedullary haematopoiesis in beta-thalassaemia intermedia.
Nucl Med Rev Cent East Eur. 2008;11(1):34-6.
8
A large intrathoracic extramedullary hematopoiesis in alpha-thalassemia: A case report.α地中海贫血合并巨大胸内髓外造血：一例报告
Medicine (Baltimore). 2019 Nov;98(44):e17612. doi: 10.1097/MD.0000000000017612.
9
Intrathoracic and pelvic extramedullary haematopoiesis in sickle cell disease: a case report.镰状细胞病患者的胸腔和盆腔髓外造血：一例报告
West Indian Med J. 2007 Dec;56(6):540-3.
10
Imaging features of focal intrahepatic extramedullary haematopoiesis.局灶性肝内髓外造血的影像学特征。
Br J Radiol. 1999 Sep;72(861):906-10. doi: 10.1259/bjr.72.861.10645201.
引用本文的文献
1
A case report of mediastinal extramedullary hematopoiesis: imaging, pathological and thoracoscopic biopsy correlation.纵隔髓外造血：影像学、病理学和胸腔镜活检相关性的病例报告。
J Cardiothorac Surg. 2024 Oct 21;19(1):609. doi: 10.1186/s13019-024-03117-8.
2
A large intrathoracic extramedullary hematopoiesis in alpha-thalassemia: A case report.α地中海贫血合并巨大胸内髓外造血：一例报告
Medicine (Baltimore). 2019 Nov;98(44):e17612. doi: 10.1097/MD.0000000000017612.
3
Intrathoracic extramedullary hematopoiesis presenting as tumor-simulating lesions of the mediastinum in α-thalassemia: A case report.α地中海贫血中表现为纵隔肿瘤样病变的胸内髓外造血：一例报告
Oncol Lett. 2015 Oct;10(4):1993-1996. doi: 10.3892/ol.2015.3597. Epub 2015 Aug 12.
本文引用的文献
1
Thalassemia.地中海贫血
Hematology Am Soc Hematol Educ Program. 2004:14-34. doi: 10.1182/asheducation-2004.1.14.
2
Intrathoracic extramedullary haematopoiesis complicated by massive haemothorax in alpha-thalassaemia.α地中海贫血合并大量血胸的胸腔内髓外造血
Thorax. 1999 May;54(5):466-8. doi: 10.1136/thx.54.5.466.
3
Spinal cord compression secondary to extramedullary hematopoiesis in thalassemia intermedia.中间型地中海贫血继发于髓外造血的脊髓压迫症
Eur Spine J. 1998;7(6):501-4. doi: 10.1007/s005860050114.
4
Diagnostic approach to mediastinal masses.纵隔肿块的诊断方法。
Eur J Radiol. 1998 Mar;27(1):21-42. doi: 10.1016/s0720-048x(97)00152-6.
5
Extramedullary hematopoiesis manifesting as a symptomatic pleural effusion.表现为有症状胸腔积液的髓外造血
Mayo Clin Proc. 1995 Dec;70(12):1161-4. doi: 10.4065/70.12.1161.
6
Intrathoracic extramedullary hematopoiesis: report of a case in a patient with sickle-cell disease-beta-thalassemia.
Am J Clin Pathol. 1980 Jan;73(1):133-7. doi: 10.1093/ajcp/73.1.133.
7
Massive hemothorax due to intrathoracic extramedullary hematopoiesis in a patient with thalassemia intermedia.中间型地中海贫血患者因胸内髓外造血导致大量血胸。
Chest. 1988 Sep;94(3):658-60. doi: 10.1378/chest.94.3.658.
8
Intrathoracic extramedullary hematopoietic tumor in hemoglobin H disease.血红蛋白H病中的胸内髓外造血肿瘤。
Am J Hematol. 1992 Dec;41(4):285-8. doi: 10.1002/ajh.2830410412.
Zotero 插件