Department of Obstetrics, Gynecology, and Reproductive Sciences, Division of Reproductive Endocrinology and Infertility, University of California, San Francisco, California, USA.
Fertil Steril. 2013 May;99(6):1476-84. doi: 10.1016/j.fertnstert.2013.03.029.
The patients referred for fertility preservation owing to a malignant disease do not represent the typical population of subfertile patients treated in IVF units. Cancer may affect multiple tissues throughout the body and can result in a variety of complications during controlled ovarian stimulation. Determination of the controlled ovarian stimulation protocol and gonadotropin dose for oocyte/embryo cryopreservation requires an individualized assessment. This review highlights the new protocols that are emerging to reduce time constraints and emphasizes management considerations to decrease complications.
因恶性疾病而接受生育力保存治疗的患者并不能代表在 IVF 中心接受治疗的典型的生育力低下患者群体。癌症可能会影响全身的多种组织,并且在控制性卵巢刺激期间可能导致多种并发症。确定控制性卵巢刺激方案和促性腺激素剂量以进行卵母细胞/胚胎冷冻保存需要进行个体化评估。本综述强调了正在出现的新方案,以减少时间限制,并强调了降低并发症的管理注意事项。