Fukushi Ken, Koie Takuya, Yamamoto Hayato, Okamoto Akiko, Imai Atsushi, Hatakeyama Shingo, Yoneyama Takahiro, Hashimoto Yasuhiro, Ohyama Chikara
The Department of Urology, Hirosaki University Graduate School of Medicine, Japan.
Hinyokika Kiyo. 2013 Apr;59(4):247-50.
A 61-year-old man was referred to our hospital complaining of elevated serum prostate-specific antigen (PSA) (5.1 ng/ml). Histopathologic diagnosis with trans-rectal prostate biopsy specimen was adenocarcinoma, Gleason score 4+5 = 9. Bone scintigraphy revealed an abnormal uptake on left coxal bone. The patient was diagnosed with prostate cancer with bone metastasis. He received androgen deprivation therapy for two years. Serum PSA decreased to an undetected level. However, the abnormal activity of left coxal bone lesion was not changed on bone scintigraphy. Coxal bone biopsy was performed. The bone lesion was histopathologically diagnosed as Paget's disease of bone.
一名61岁男性因血清前列腺特异性抗原(PSA)升高(5.1 ng/ml)转诊至我院。经直肠前列腺活检标本的组织病理学诊断为腺癌,Gleason评分4+5 = 9。骨闪烁显像显示左髋骨有异常摄取。该患者被诊断为前列腺癌伴骨转移。他接受了两年的雄激素剥夺治疗。血清PSA降至检测不到的水平。然而,骨闪烁显像显示左髋骨病变的异常活性未改变。进行了髋骨活检。骨病变经组织病理学诊断为佩吉特骨病。