Gastroenterology and Liver Unit, Royal Hallamshire Hospital, Sheffield Teaching Hospitals, Sheffield, United Kingdom.
Clin Gastroenterol Hepatol. 2013 Nov;11(11):1445-50. doi: 10.1016/j.cgh.2013.04.025. Epub 2013 Apr 29.
BACKGROUND & AIMS: There are few data on outcomes and mortality of patients who have received gastrostomies. We assessed 30-day and 1-year mortalities of patients in the United Kingdom who were referred to hospitals for gastrostomies and of patients who deferred this intervention.
We collected data from 1327 patients referred to 2 hospitals in Sheffield, United Kingdom, for gastrostomies from February 2004 through May 2010. Data were analyzed to determine 30-day and 1-year mortalities. Predicted mortality by using the validated Sheffield Gastrostomy Scoring System (SGSS) was then compared with actual mortality by using area under the receiver operator curves to determine levels of agreement in patients referred for gastrostomy.
Three hundred four patients (23%) did not undergo gastrostomy after multidisciplinary team discussion, which was based on physicians' recommendations. This group had 35.5% mortality at 30 days and 74.3% at 1 year, whereas mortality among patients who underwent gastrostomy (n = 1027) was 11.2% at 30 days and 41.1% at 1 year (P < .0001, compared with patients who deferred the procedure). The area under the receiver operator curves for the SGSS demonstrated acceptable agreement between predicted and actual mortality in patients who underwent or were deferred gastrostomy.
On the basis of data from 1327 patients, those who undergo gastrostomy have significantly lower mortality than those who defer the procedure. Without applying the SGSS, clinicians are able to select patients most likely to benefit from gastrostomy. The SGSS could provide objective support to clinicians involved in making ethically contentious or potentially litigious decisions.
接受胃造口术患者的预后和死亡率数据较少。我们评估了英国因胃造口术而转诊至医院的患者以及延迟该干预的患者的 30 天和 1 年死亡率。
我们从 2004 年 2 月至 2010 年 5 月在英国谢菲尔德的 2 家医院收集了 1327 名因胃造口术而转诊的患者的数据。分析数据以确定 30 天和 1 年的死亡率。然后,使用验证的谢菲尔德胃造口术评分系统(SGSS)预测死亡率,并使用接收者操作特征曲线下面积来比较实际死亡率,以确定在转诊进行胃造口术的患者中,预测死亡率与实际死亡率的一致性程度。
多学科团队讨论后,有 304 名患者(23%)未进行胃造口术,这是基于医生的建议。该组在 30 天时的死亡率为 35.5%,1 年时为 74.3%,而接受胃造口术的患者(n=1027)的死亡率为 30 天时为 11.2%,1 年时为 41.1%(P<0.0001,与延迟该手术的患者相比)。在接受或延迟胃造口术的患者中,SGSS 的接收者操作特征曲线下面积表明预测死亡率与实际死亡率之间具有可接受的一致性。
基于 1327 名患者的数据,接受胃造口术的患者的死亡率明显低于延迟该手术的患者。如果不使用 SGSS,临床医生可以选择最有可能从胃造口术受益的患者。SGSS 可以为参与做出具有道德争议或潜在法律纠纷的决策的临床医生提供客观支持。