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经皮内镜下胃造口术后死亡:全国患者结局与死亡保密调查结果

Death after PEG: results of the National Confidential Enquiry into Patient Outcome and Death.

作者信息

Johnston Simon D, Tham Tony C K, Mason Marisa

机构信息

Department of Gastroenterology, Belfast City Hospital, Northern Ireland.

出版信息

Gastrointest Endosc. 2008 Aug;68(2):223-7. doi: 10.1016/j.gie.2007.10.019. Epub 2008 Mar 7.

Abstract

BACKGROUND

Percutaneous endoscopic gastrostomy (PEG) is an accepted method of placing a feeding tube to enable enteral feeding in patients with swallowing difficulties. However, the factors associated with complications and death after PEG have not been studied in detail. We describe the largest audit of deaths after PEG tube insertion.

OBJECTIVE

Our purpose was to determine the factors associated with death after PEG tube insertion.

DESIGN

Deaths occurring within 30 days after PEG tube insertion in the United Kingdom between April 2002 and March 2003 were identified and a questionnaire was sent to the consultant endoscopist for completion.

PATIENTS

A total of 719 patients (391 male, median age 80 years, range 26-98 years) who died within 30 days after PEG insertion were identified for this study.

SETTING

United Kingdom hospitals.

MAIN OUTCOME MEASUREMENT

Cause of death.

RESULTS

A total of 97% of the identified patients had coexistent neurologic disease. PEG tubes were inserted by specialized GI physicians in 522 cases (73%). Seventy-two patients (10%) required reversal agents after sedation. After PEG tube insertion, 309 patients (43%) died within 1 week. Death was due to cardiovascular disease (n = 175), respiratory disease (n = 508), central nervous system disease (n = 358), renal disease (n = 38), and hepatic failure (n = 11). In 136 cases (19%) the National Confidential Enquiry into Patient Outcome and Death expert panel regarded the procedure as futile.

LIMITATIONS

Retrospective review of case records.

CONCLUSIONS

Mortality and morbidity rates after PEG tube insertion are not insignificant. Selection of patients is paramount to good patient outcomes. Multidisciplinary team assessment should be performed on all patients being referred for PEG tube insertion.

摘要

背景

经皮内镜下胃造口术(PEG)是一种公认的为吞咽困难患者置入饲管以实现肠内营养的方法。然而,PEG术后并发症及死亡相关因素尚未得到详细研究。我们描述了规模最大的PEG置管术后死亡情况审计。

目的

我们的目的是确定PEG置管术后死亡相关因素。

设计

确定2002年4月至2003年3月在英国PEG置管术后30天内发生的死亡病例,并向内镜顾问医师发送问卷以完成调查。

患者

本研究共纳入719例在PEG置管术后30天内死亡的患者(男性391例,中位年龄80岁,范围26 - 98岁)。

地点

英国医院。

主要观察指标

死亡原因。

结果

共97%的确诊患者合并神经系统疾病。522例(73%)PEG管由专科胃肠病医师置入。72例患者(10%)在镇静后需要使用逆转剂。PEG置管术后,309例患者(43%)在1周内死亡。死亡原因包括心血管疾病(n = 175)、呼吸系统疾病(n = 508)、中枢神经系统疾病(n = 358)、肾脏疾病(n = 38)和肝衰竭(n = 11)。136例(19%)病例中,国家患者结局与死亡保密调查专家小组认为该操作无效。

局限性

病例记录的回顾性研究。

结论

PEG置管术后的死亡率和发病率不容小觑。患者的选择对于良好的治疗结局至关重要。对于所有转诊接受PEG置管的患者,均应进行多学科团队评估。

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