Yang Y B
Ear, Nose and Throat Institute of Shanghai Medical University.
Zhonghua Er Bi Yan Hou Ke Za Zhi. 1990;25(1):42-4, 63.
The NK activity has been examined in a 4-hour 51Cr release assay in 59 untreated patients with laryngeal carcinoma, 46 untreated patients with nasopharyngeal carcinoma and 18 untreated patients with other head and neck carcinomas. The kinetic changes of NK activity in 10 patients with laryngeal carcinoma before and after surgery was also observed. The results showed that the NK activity of patients was significantly lower than that of the normal control and decreased progressively in the advanced cases. A significant decrease in NK activity in laryngeal carcinoma patients was found 3-5 days after surgery, and an increase in activity was seen more than one week later. These results suggest that the test of NK activity in untreated laryngeal carcinoma patients might be a parameter to predict the course and prognosis of the disease.
在一项4小时51铬释放试验中，对59例未经治疗的喉癌患者、46例未经治疗的鼻咽癌患者和18例未经治疗的其他头颈癌患者的自然杀伤（NK）活性进行了检测。还观察了10例喉癌患者手术前后NK活性的动态变化。结果显示，患者的NK活性显著低于正常对照组，且在晚期病例中逐渐降低。喉癌患者术后3至5天NK活性显著下降，而术后一周多活性则有所增加。这些结果表明，检测未经治疗的喉癌患者的NK活性可能是预测该疾病进程和预后的一个参数。
