Division Physical Medicine and Rehabilitation, University of Alberta, 10230 111 Avenue, Edmonton T5G 0B7, Canada.
Muscle Nerve. 2013 Jul;48(1):122-6. doi: 10.1002/mus.23725. Epub 2013 May 3.
A single local corticosteroid injection is an effective treatment for carpal tunnel syndrome. No study has specifically examined the effectiveness of a second injection on relapse after primary injection.
We identified a cohort of patients who had received an initial corticosteroid injection into 1 wrist and then, at a later date, a second injection into the same wrist. We compared the change in the Boston Symptom Severity Scale (SSS) and Functional Status Scale (FSS) between first and second injections.
In 229 patients who received 2 injections the mean improvement on the SSS was 1.2 (SD = 0.8) for the first injection and 1.3 (SD = 0.9) for the second, which was not statistically significant. Improvement in FSS for the first injection was 0.4 (SD = 0.8) and 0.7 (SD = 0.8) for the second, which was statistically significant (P < 0.001).
Second corticosteroid injections appear to be at least as effective as the first.
单次局部皮质类固醇注射是治疗腕管综合征的有效方法。尚无研究专门探讨初次注射后再次注射的复发效果。
我们确定了一组患者，他们的 1 只手腕接受了初始皮质类固醇注射，然后在稍后的日期对同一只手腕进行了第二次注射。我们比较了首次和第二次注射之间 Boston 症状严重程度量表（SSS）和功能状态量表（FSS）的变化。
在接受 2 次注射的 229 名患者中，首次注射的 SSS 平均改善为 1.2（SD=0.8），第二次注射的 SSS 平均改善为 1.3（SD=0.9），差异无统计学意义。首次注射的 FSS 改善为 0.4（SD=0.8），第二次注射的 FSS 改善为 0.7（SD=0.8），差异具有统计学意义（P<0.001）。
第二次皮质类固醇注射似乎至少与第一次一样有效。
