Garge Saurabh, Bawa Monika, Kanojia Ravi P, Gupta Kirti, Rao Kattragadda Laxmi Narain
Department of Pediatric Surgery, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, India.
J Pediatr Endocrinol Metab. 2013;26(5-6):599-603. doi: 10.1515/jpem.2011.343.
Adrenocortical carcinoma (ACC) is a rare malignancy in children. Most of these are endocrinologically active tumors, with virilizing features being typically dominant. Its presentation with isolated Cushing syndrome is rare. We report a 3-month-old infant with Cushing syndrome without the clinical features of androgen or mineralocorticoid excess consequently diagnosed with ACC. We discuss the different presentations, diagnosis, and management of this rare tumor with a rarer presentation.
肾上腺皮质癌（ACC）是儿童中一种罕见的恶性肿瘤。其中大多数是具有内分泌活性的肿瘤，以男性化特征为主。其以孤立性库欣综合征表现较为罕见。我们报告一例3个月大的患有库欣综合征的婴儿，无雄激素或盐皮质激素过多的临床特征，最终诊断为肾上腺皮质癌。我们讨论了这种罕见肿瘤的不同表现、诊断及治疗，且此肿瘤表现更为罕见。
