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[小鼠肝癌中肝细胞质膜抗原B10的超微结构定位]

[The ultrastructural localization of antigen B10 of the hepatocyte plasma membrane in mouse hepatomas].

作者信息

Kondalenko V F, Kuprina N I

出版信息

Biull Eksp Biol Med. 1990 Mar;109(3):292-5.

PMID:2364158
Abstract

The ultrastructure of the murine hepatocyte plasma membrane antigen (Ag B10) was studied by immunoelectron microscopy in 5 spontaneous and 3 chemical-induced hepatomas. Ag B10 was associated with plasmalemma of bile canaliculi and membrane of microvilli as in normal liver. Sometimes it was connected with plasmalemma of lateral domain of tumor cells. The availability of Ag B10 in the matrix of bile canaliculi and within microvilli was shown.

摘要

通过免疫电子显微镜对5例自发性肝癌和3例化学诱导性肝癌研究了小鼠肝细胞质膜抗原(Ag B10)的超微结构。与正常肝脏一样,Ag B10与胆小管的质膜和微绒毛膜相关。有时它与肿瘤细胞侧面区域的质膜相连。显示了Ag B10在胆小管基质和微绒毛内的存在情况。

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