Department of Neurology, University of Kansas Medical Center, 3599 Rainbow Boulevard, Mail-Stop 2012, Kansas City, KS 66160, USA.
Neurol Clin. 2013 May;31(2):447-62. doi: 10.1016/j.ncl.2013.02.003. Epub 2013 Mar 15.
Diabetic neuropathies consist of a variety of syndromes resulting from different types of damage to peripheral or cranial nerves. Although distal symmetric polyneuropathy is the most common type of diabetic neuropathy, many other subtypes have been defined since the 1800s, including proximal diabetic, truncal, cranial, median, and ulnar neuropathies. Various theories have been proposed for the pathogenesis of these neuropathies. The treatment of most requires tight and stable glycemic control. Spontaneous recovery is seen in most of these conditions with diabetic control. Immunotherapies have been tried in some of these conditions however are controversial.
糖尿病性神经病变包括多种综合征,由周围或颅神经的不同类型损伤引起。虽然远端对称性多发性神经病是最常见的糖尿病性神经病变类型,但自 19 世纪以来已经定义了许多其他亚型,包括近端糖尿病性、躯干性、颅神经性、正中神经性和尺神经性神经病。对于这些神经病变的发病机制提出了各种理论。大多数情况下需要严格和稳定的血糖控制来治疗。随着糖尿病的控制,大多数情况下这些疾病都会出现自发恢复。一些情况下已经尝试了免疫疗法,但存在争议。