糖尿病神经病变第 1 部分：概述和对称表型。
Diabetic neuropathy part 1: overview and symmetric phenotypes.
机构信息
Department of Neurology, University of Kansas Medical Center, Kansas City, KS, USA.
出版信息
Neurol Clin. 2013 May;31(2):425-45. doi: 10.1016/j.ncl.2013.02.004. Epub 2013 Mar 15.
Abstract
Diabetes is the most common cause of neuropathy in United States and neuropathies are the most common complication of diabetes mellitus, affecting up to 50% of patients with type 1 and type 2 diabetes mellitus. Symptoms usually include numbness, tingling, pain, and weakness. Dizziness with postural changes can be seen with autonomic neuropathy. Metabolic, vascular, and immune theories have been proposed for the pathogenesis of diabetic neuropathy. Axonal damage and segmental demyelination can be seen with diabetic neuropathies. Management of diabetic neuropathy should begin at the initial diagnosis of diabetes and mainly requires tight and stable glycemic control.
摘要
糖尿病是美国最常见的神经病变原因，而神经病变是糖尿病最常见的并发症，影响多达 50%的 1 型和 2 型糖尿病患者。症状通常包括麻木、刺痛、疼痛和无力。体位改变时头晕可能与自主神经病变有关。代谢、血管和免疫理论被提出用于解释糖尿病性神经病变的发病机制。糖尿病性神经病变可出现轴索性损伤和节段性脱髓鞘。糖尿病神经病变的管理应在糖尿病初始诊断时开始，主要需要严格和稳定的血糖控制。
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