University of the West Indies, Mona, Tropical Medicine Research Institute, Sickle Cell Unit, Kingston, Jamaica.
C R Biol. 2013 Mar;336(3):159-63. doi: 10.1016/j.crvi.2012.09.007. Epub 2012 Oct 30.
A common observation in sickle cell disease is growth retardation, in particular, wasting. Wasting is associated with increased hospitalization and possibly poorer clinical outcomes. Therefore understanding the mechanism of wasting is crucial and reducing the degree of wasting by improving the nutritional status, holds the potential for modifying the course of the disease.
镰状细胞病的一个常见观察结果是生长迟缓,特别是消瘦。消瘦与住院率增加和可能更差的临床结局有关。因此,了解消瘦的机制至关重要,通过改善营养状况来减少消瘦的程度,有可能改变疾病的进程。