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人类根龋:晚期病变的组织病理学

Human root caries: histopathology of advanced lesions.

作者信息

Schüpbach P, Guggenheim B, Lutz F

机构信息

Department of Oral Microbiology and General Immunology, University of Zurich, Switzerland.

出版信息

Caries Res. 1990;24(3):145-58. doi: 10.1159/000261258.

DOI:10.1159/000261258
PMID:2364398
Abstract

The histopathology of human root caries was examined in extracted teeth. The present study details several stages of advanced carious lesions in root dentin. Lesions of different severities were assessed by different optical methods. Four major root caries patterns were defined and significant differences between coronal and root caries elucidated. The patterns were distinguishable by (1) their location at the exposed root surface, (2) their mode of spreading towards the root canal and over the root surface, (3) their mode of bacterial spreading in dentin and (4) the role of dentinal defense mechanisms. In addition, a comparison of clinical and histological classification of lesions revealed that the carious process extended much deeper towards the root canal and had a higher degree of both bacterial infection and dentin demineralization than could be predicted by clinical examination.

摘要

在拔除的牙齿中检查了人类根龋的组织病理学。本研究详细描述了根牙本质中晚期龋损的几个阶段。通过不同的光学方法评估了不同严重程度的病变。定义了四种主要的根龋模式,并阐明了冠龋和根龋之间的显著差异。这些模式可通过以下方式区分:(1)它们在暴露根表面的位置;(2)它们向根管和根表面扩散的方式;(3)它们在牙本质中细菌扩散的方式;(4)牙本质防御机制的作用。此外,病变临床分类与组织学分类的比较表明,龋病进程向根管延伸得更深,细菌感染和牙本质脱矿程度均高于临床检查的预测。

相似文献

1
Human root caries: histopathology of advanced lesions.人类根龋:晚期病变的组织病理学
Caries Res. 1990;24(3):145-58. doi: 10.1159/000261258.
2
Human root caries: histopathology of arrested lesions.人类根龋:静止性损害的组织病理学
Caries Res. 1992;26(3):153-64. doi: 10.1159/000261436.
3
Human root caries: histopathology of initial lesions in cementum and dentin.人类根龋:牙骨质和牙本质初始病变的组织病理学
J Oral Pathol Med. 1989 Mar;18(3):146-56. doi: 10.1111/j.1600-0714.1989.tb00753.x.
4
Histopathology of root surface caries.根面龋的组织病理学
J Dent Res. 1990 May;69(5):1195-204. doi: 10.1177/00220345900690051601.
5
[Root caries--scanning electron microscopic observations].[根龋——扫描电子显微镜观察]
Zahn Mund Kieferheilkd Zentralbl. 1990;78(8):699-703.
6
Ultrastructural study on human root caries.
Caries Res. 1989;23(4):209-17. doi: 10.1159/000261180.
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Ecological Hypothesis of Dentin and Root Caries.牙本质和根龋的生态学假说
Caries Res. 2016;50(4):422-31. doi: 10.1159/000447309. Epub 2016 Jul 27.
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Relationship between the color of carious dentin with varying lesion activity, and bacterial detection.不同病变活性的龋损牙本质颜色与细菌检测之间的关系
J Dent. 2008 Feb;36(2):143-51. doi: 10.1016/j.jdent.2007.11.012. Epub 2008 Jan 8.
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Micromorphological and micronanalytical characterization of stagnating and progressing root caries lesions.静止性和进展性根龋损害的微观形态学和微分析特征
Arch Oral Biol. 2007 Jun;52(6):591-7. doi: 10.1016/j.archoralbio.2006.11.008. Epub 2006 Dec 19.
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J Dent Res. 1985 May;64(5):804-9. doi: 10.1177/00220345850640050401.

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Gene expression of bacterial collagenolytic proteases in root caries.根龋中细菌胶原溶解蛋白酶的基因表达
J Oral Microbiol. 2018 Jan 18;10(1):1424475. doi: 10.1080/20002297.2018.1424475. eCollection 2018.