Gao Hua, Gu You-You, Qiu Ming-cai
Department of Endocrinology, Tianjin Medical University General Hospital, China.
Neuro Endocrinol Lett. 2013;34(2):102-6.
Autoimmune hypophysitis (AH) is commonly believed to be a rare chronic inflammatory condition of the pituitary gland. In clinical practice, however, the disease is often seen indeed. It typically presents with hypopituitarism and pituitary mass found by MRI. We report here unusual presentations of two females with AH followed by empty sella syndrome. The two females, aged at 64 and 57-years-old, presented with anterior pituitary dysfunction, diplopia and diabetes insipidus. By MRI the two patients shared the common characteristics with diffuse homogenous contrast enhancement of the gland and increased stalk thickness. After a long period treatment with glucocorticoids, empty sella was eventually detected by MRI.
自身免疫性垂体炎（AH）通常被认为是一种罕见的垂体慢性炎症性疾病。然而，在临床实践中，这种疾病实际上并不少见。它通常表现为垂体功能减退和通过磁共振成像（MRI）发现的垂体肿块。我们在此报告两例患有AH并随后出现空蝶鞍综合征的女性患者的不寻常表现。这两名女性患者年龄分别为64岁和57岁，表现为垂体前叶功能障碍、复视和尿崩症。通过MRI检查，这两名患者具有共同特征，即垂体弥漫性均匀强化和垂体柄增厚。在接受长期糖皮质激素治疗后，最终通过MRI检测到空蝶鞍。
