利妥昔单抗和苯达莫司汀在终末期肾病（ESRD）患者慢性淋巴细胞白血病（CLL）治疗中的应用。
The use of rituximab and bendamustine in treating chronic lymphocytic leukaemia (CLL) in end-stage renal disease (ESRD).
作者信息
Shoji Jun, Lew Susie Q
机构信息
Department of Medicine, George Washington University, Washington, DC, USA.
出版信息
BMJ Case Rep. 2013 May 2;2013:bcr2013009637. doi: 10.1136/bcr-2013-009637.
Abstract
A patient with a history of type 2 diabetes mellitus and chronic lymphocytic leukaemia has renal failure with large kidneys. The patient refused kidney biopsy to determine the aetiology of her renal failure. She uses peritoneal dialysis to treat renal failure. She received rituximab and bendamustine to treat chronic lymphocytic leukaemia. Adenopathy resolves with treatment and she does not experience any electrolyte disturbances or decrease in urine output as a result of chemotherapy in the setting of renal failure. Renal function did not recover with chemotherapy.
摘要
一位患有2型糖尿病和慢性淋巴细胞白血病的患者出现肾衰竭，肾脏肿大。患者拒绝进行肾活检以确定肾衰竭的病因。她采用腹膜透析治疗肾衰竭。她接受了利妥昔单抗和苯达莫司汀治疗慢性淋巴细胞白血病。淋巴结病经治疗后消退，在肾衰竭情况下，她未因化疗出现任何电解质紊乱或尿量减少。化疗后肾功能未恢复。
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