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高磷血症性肿瘤性钙化症

Hyperphosphatemic tumoral calcinosis.

作者信息

Mallick Saumyaranjan, Ahmad Zohra, Gupta Arun K, Mathur Sandeep R

机构信息

Department of Pathology, All India Institute of Medical Sciences, New Delhi, India.

出版信息

BMJ Case Rep. 2013 May 3;2013:bcr2013008728. doi: 10.1136/bcr-2013-008728.

Abstract

Tumoral calcinosis (TC) is a rare locally aggressive lesion characterised by extra-articular soft tissue deposition of the calcium phosphate around large joints. The exact aetiology is not known. A 19-year-old boy presented with a painful progressive swelling around the bilateral elbow and left hip joints over a 6-month duration. Routine laboratory results showed a normal haemogram, and normal calcium and high phosphate levels. Imaging showed a soft tissue calcified mass around these joints. The cut surface of the excised mass showed myxoid material with areas of calcification. On microscopy, there were typical features of TC. Our case is being presented due to the rarity of the entity and the peculiar dual energy CT (DECT) finding which are being described for the first time in this pathology.

摘要

肿瘤性钙化(TC)是一种罕见的局部侵袭性病变,其特征为大关节周围关节外软组织中磷酸钙沉积。确切病因尚不清楚。一名19岁男孩在6个月的时间里双侧肘部和左髋关节周围出现疼痛性进行性肿胀。常规实验室检查结果显示血常规正常,钙水平正常,磷水平升高。影像学检查显示这些关节周围有软组织钙化肿块。切除肿块的切面显示为有钙化区域的黏液样物质。显微镜检查显示有TC的典型特征。由于该病例罕见且具有独特的双能CT(DECT)表现,而这在本病理学中是首次描述,故予以报道。

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