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[老年人脑血管疾病——73例脑出血尸检病例的临床病理研究]

[Cerebrovascular disease in the elderly--a clinicopathological study of 73 autopsied cases with intracerebral hemorrhage].

作者信息

Kawahata N

机构信息

Department of Neurology, Yokufukai Geriatric Hospital.

出版信息

Rinsho Shinkeigaku. 1990 Mar;30(3):276-81.

PMID:2364629
Abstract

The medical records and autopsy data of patients over the age of 70 years at death with a diagnosis of intracerebral hemorrhage (ICH) in the Yokufukai Geriatric Hospital were reviewed. All cases with ICH caused by head injury, rupture aneurysms or arteriovenous malformations were excluded from this study. There were 73 autopsied cases with spontaneous ICH from January 1978 to September 1988. There were 33 men and 40 women. Fourteen percent of the patients had a stroke while hospitalized for another disorder. Their ages at death ranged from 70 to 99 years with a mean of 81.8 years. Of these, 48 cases (66%) were 70 years or older at the time of ICH. In the senile ICH (over 70 years), the following characteristics were observed; (1) the most common location was the thalamus, which accounted for 33.3% of the hemorrhage. (2) subcortical and cerebellar hemorrhage accounted for 16.6% and 14.6% of the total, respectively. (3) there was no pontine hemorrhage. Fifty-seven percent had anamnestic hypertension before the stroke. The ages at which they became bedridden state ranged from 62 to 92 years with a mean of 79.5 years. This study revealed that the non-organic factors such as insidious generalized muscular weakness or decreased spontaneity were important as causes of the deterioration of ADL in the chronic stage of the senile ICH. Within one year after becoming bedridden state, 76.1% of all patients died. The bedridden state in the elderly with the residuals of ICH indicated a poor prognosis. As causes of death, pneumonia occurred in 28.8% of all patients, brain death in 19.2%, and sudden death in 12.3%.

摘要

回顾了横福会老年医院70岁及以上死亡且诊断为脑出血(ICH)患者的病历和尸检数据。本研究排除了所有因头部受伤、动脉瘤破裂或动静脉畸形导致脑出血的病例。1978年1月至1988年9月期间有73例自发性脑出血尸检病例。其中男性33例,女性40例。14%的患者在因其他疾病住院期间发生了中风。他们的死亡年龄在70至99岁之间,平均年龄为81.8岁。其中,48例(66%)在脑出血时年龄在70岁及以上。在老年脑出血(70岁以上)中,观察到以下特征:(1)最常见的部位是丘脑,占出血的33.3%。(2)皮质下和小脑出血分别占总数的16.6%和14.6%。(3)没有桥脑出血。57%的患者在中风前有既往高血压病史。他们卧床的年龄在62至92岁之间,平均年龄为79.5岁。本研究表明,隐匿性全身肌无力或自发性降低等非器质性因素是老年脑出血慢性期日常生活活动能力恶化的重要原因。在卧床状态出现后的一年内,所有患者中有76.1%死亡。有脑出血后遗症的老年人卧床状态预后较差。作为死亡原因,28.8%的患者发生了肺炎,19.2%发生了脑死亡,12.3%发生了猝死。

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