Perks Teleri, Popat Hashmat, Cronin Andrew J, Durning Peter, Maggs Roger
Department of Orthodontics, University Dental Hospital, Health Park, Cardiff, United Kingdom.
Orthodontics (Chic.). 2013;14(1):e168-76. doi: 10.11607/ortho.897.
Zimmermann-Laband syndrome (ZLS) is a rare autosomal disorder characterized by gingival fibromatosis, abnormalities of the nose and/or ears, hypoplasia of the nails or terminal phalanges of the hands and feet, hyperextensibility of joints, hepatosplenomegaly, hirsutism, and intellectual disability. The characteristics of the syndrome are highly variable and complicated. This paper reports a case of ZLS and the clinical manifestations encountered in relation to the current available literature. The comprehensive management of the patient's dentition is described, focusing on the orthodontic and surgical considerations clinicians should be aware of when treating patients with the syndrome.
齐默尔曼-拉班德综合征（ZLS）是一种罕见的常染色体疾病，其特征为牙龈纤维瘤病、鼻和/或耳异常、指甲或手足末端指骨发育不全、关节过度伸展、肝脾肿大、多毛症和智力残疾。该综合征的特征高度可变且复杂。本文报告了一例ZLS病例以及与现有文献相关的临床表现。描述了患者牙列的综合管理，重点关注临床医生在治疗该综合征患者时应注意的正畸和手术方面的考虑因素。
