Neuroimaging Laboratory, Department of Neurology, University of Campinas, Campinas, SP, Brazil.
Epilepsia. 2013 May;54 Suppl 2:67-70. doi: 10.1111/epi.12188.
Neuroimaging techniques in epilepsy are used widely for definition of the epileptogenic lesion and surgical decision. However, its applications extend to the knowledge of epileptic mechanisms and include the identification of prognostic features that can help our decisions on the appropriate type of treatment on an individual basis. Structural neuroimaging may be able to identify patients more likely to respond to antiepileptic drug (AED) treatment and also patients who are better candidates for earlier surgical treatment. In the past decades, quantitative analyses have also improved our knowledge about epileptogenic lesions and networks as well as the following prognoses: seizure control, cognitive outcome, and comorbidities. New advanced neuroimaging techniques such as functional magnetic resonance imaging (MRI) and the development biotracers that could be associated with inflammation and specific genetic patterns will add further knowledge to the development of epilepsy treatments.
神经影像学技术在癫痫中的应用广泛，用于确定致痫病灶和手术决策。然而，其应用范围延伸至了解癫痫机制，并包括识别预测特征，这些特征有助于我们根据个体情况做出适当的治疗类型决策。结构性神经影像学可能能够识别更有可能对抗癫痫药物（AED）治疗有反应的患者，以及更适合早期手术治疗的患者。在过去的几十年中，定量分析也提高了我们对致痫病灶和网络的认识，以及以下预后：癫痫发作控制、认知结果和合并症。新的先进神经影像学技术，如功能磁共振成像（MRI）和开发与炎症和特定遗传模式相关的生物示踪剂，将为癫痫治疗的发展提供更多的知识。
