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1%托吡卡胺所致瞳孔散大和睫状肌麻痹对成年马球面屈光的影响。

The effect of 1% tropicamide-induced mydriasis and cycloplegia on spherical refraction of the adult horse.

作者信息

McMullen Richard J, Davidson Michael G, Gilger Brian C

机构信息

Department of Clinical Sciences, North Carolina State University, Raleigh, NC, USA.

出版信息

Vet Ophthalmol. 2014 Mar;17(2):120-5. doi: 10.1111/vop.12055. Epub 2013 May 6.

DOI:10.1111/vop.12055
PMID:23647634
Abstract

OBJECTIVES

To determine the effects of tropicamide 1% on the refractive state of the adult equine globe and identify the most appropriate time period (in relation to mydriasis) to perform streak retinoscopy.

ANIMALS STUDIED

Eight university-owned mares of various ages and breeds.

PROCEDURES

Topical tropicamide 1% was applied to one randomly selected eye from each of the horses to induce mydriasis and cycloplegia. The contralateral eyes served as controls. Streak retinoscopy and pupillometry were performed prior to, and every 5 min after tropicamide 1% installation for 90 min.

RESULTS

All values are expressed as mean ± SD. Both horizontal (2.8 ± 0.74 mm) and vertical (7.3 ± 1.29 mm) mean pupil diameters increased significantly (P < 0.04) in the treatment eyes compared with the control eyes (horizontal [0.48 ± 0.85 mm] and vertical [1.06 ± 1.31 mm] pupil diameter). No significant differences in the refractive states of the treatment (horizontal: +0.25 ± 0.43 D and vertical: +0.41 ± 0.37 D) or control (horizontal: +0.34 ± 0.39 D and vertical: +0.41 ± 0.37 D) eyes were identified at any time point. Three of the eight treatment eyes demonstrated blurry or reversing streak reflexes during streak retinoscopy evaluation following the application of topical tropicamide 1%.

CONCLUSIONS

While these reflexes did not significantly influence streak retinoscopy results, their presence may subjectively influence a novice retinoscopist's ability to obtain accurate results. Therefore, optimal streak retinoscopy results may be obtained prior to, or 40- to 45-min following the application of topical tropicamide 1%, once near-maximal dilation has been achieved.

摘要

目的

确定1%托吡卡胺对成年马眼球屈光状态的影响,并确定进行带状检影验光的最合适时间段(与散瞳相关)。

研究动物

8匹不同年龄和品种的大学-owned母马。

方法

对每匹马随机选择的一只眼睛局部应用1%托吡卡胺以诱导散瞳和睫状肌麻痹。对侧眼作为对照。在应用1%托吡卡胺前以及应用后每5分钟进行带状检影验光和瞳孔测量,持续90分钟。

结果

所有数值均以平均值±标准差表示。与对照眼(水平[0.48±0.85毫米]和垂直[1.06±1.31毫米]瞳孔直径)相比,治疗眼的水平(2.8±0.74毫米)和垂直(7.3±1.29毫米)平均瞳孔直径均显著增加(P<0.04)。在任何时间点,治疗眼(水平:+0.25±0.43屈光度和垂直:+0.41±0.37屈光度)和对照眼(水平:+0.34±0.39屈光度和垂直:+0.41±0.37屈光度)的屈光状态均无显著差异。在局部应用1%托吡卡胺后的带状检影验光评估中,8只治疗眼中有3只出现模糊或反转的带状反射。

结论

虽然这些反射并未显著影响带状检影验光结果,但其存在可能会主观影响新手检影验光师获得准确结果的能力。因此,在局部应用1%托吡卡胺前或应用后40至45分钟,一旦达到接近最大散瞳时,可获得最佳的带状检影验光结果。

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