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美国鼻出血栓塞治疗趋势:2003-2010 年全国住院患者样本研究。

Trends in epistaxis embolization in the United States: a study of the Nationwide Inpatient Sample 2003-2010.

机构信息

Department of Radiology, Mayo Clinic, Rochester, MN 55905, USA.

出版信息

J Vasc Interv Radiol. 2013 Jul;24(7):969-73. doi: 10.1016/j.jvir.2013.02.035. Epub 2013 May 3.

Abstract

PURPOSE

Endovascular embolization has emerged as a viable adjunct and alternative to surgical ligation in selected cases of epistaxis refractory to nasal packing. A large administrative database was used to study outcomes, complications, and trends in utilization of surgical and endovascular treatments for epistaxis.

MATERIALS AND METHODS

With the Nationwide Inpatient Sample from 2003 to 2010, patients with a primary diagnosis of epistaxis undergoing surgical ligation and/or endovascular embolization were identified. Trends in the use of these procedures from 2003 to 2010 were examined. Three groups of patients were defined: those who underwent (i) surgical ligation, (ii) endovascular embolization, or (iii) both. Demographic variables, comorbidities, and outcomes were compared across groups.

RESULTS

Among a total of 69,410 patients identified, 64,289 (92.6%) underwent surgical ligation alone for epistaxis, 4,440 (6.4%) underwent endovascular embolization alone, and 681 (1.0%) underwent both treatments. Use of endovascular embolization for epistaxis increased from 2.8% of cases in 2003 to 10.7% of cases in 2010 (P<.0001). Patients who underwent endovascular embolization had similar mortality rates as those who underwent surgical ligation (2.1% [93 of 4,440] vs 2.1% [1,328 of 64,289]; P = .89). Endovascular embolization was associated with significantly higher rates of stroke (0.9% [41 of 4,440] vs 0.1% [34/64,289]; P<.0001) and hematoma (1.9% [83 of 4,440] vs 0.4% [239 of 64,289]; P<.0001).

CONCLUSIONS

Use of endovascular embolization for treatment of epistaxis increased significantly between 2003 and 2010. Patients who underwent endovascular embolization had similar mortality rates but higher stroke rates compared with those who underwent surgical ligation.

摘要

目的

在某些对鼻腔填塞无效的鼻出血病例中,血管内栓塞已成为手术结扎的可行辅助手段和替代方法。本研究使用大型行政数据库来研究手术和血管内治疗鼻出血的结果、并发症和使用趋势。

材料和方法

利用 2003 年至 2010 年全国住院患者样本,确定接受手术结扎和/或血管内栓塞治疗的鼻出血患者。检查了 2003 年至 2010 年这些治疗方法的使用趋势。将患者分为三组:(i)接受手术结扎、(ii)接受血管内栓塞或(iii)两者都接受的患者。比较了各组之间的人口统计学变量、合并症和结局。

结果

在总共 69410 名患者中,64289 名(92.6%)因鼻出血单独接受手术结扎,4440 名(6.4%)单独接受血管内栓塞,681 名(1.0%)同时接受两种治疗。血管内栓塞治疗鼻出血的使用率从 2003 年的 2.8%上升到 2010 年的 10.7%(P<.0001)。接受血管内栓塞的患者的死亡率与接受手术结扎的患者相似(2.1%[4440 例中的 93 例]与 2.1%[64289 例中的 1328 例];P =.89)。血管内栓塞与更高的中风发生率相关(0.9%[4440 例中的 41 例]与 0.1%[64289 例中的 34 例];P<.0001)和血肿发生率(1.9%[4440 例中的 83 例]与 0.4%[64289 例中的 239 例];P<.0001)。

结论

2003 年至 2010 年间,血管内栓塞治疗鼻出血的使用率显著增加。接受血管内栓塞的患者死亡率相似,但中风发生率高于接受手术结扎的患者。

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