Kanazawa Hidenori, Kotoda Atsushi, Akimoto Tetsu, Shinozaki Takeshi, Inoue Makoto, Sugimoto Hideharu, Kusano Eiji
Division of Nephrology, Department of Internal Medicine, Jichi Medical University, Japan.
Intern Med. 2013;52(9):987-91. doi: 10.2169/internalmedicine.52.9204. Epub 2012 Mar 1.
Acute kidney injury (AKI) is a well-recognized complication of minimal change nephrotic syndrome (MCNS). Previous reports support the concept that AKI associated with MCNS is reversible; however, information regarding the hemodynamic basis of AKI in MCNS is insufficient. We herein describe a case of AKI in a man with MCNS. In this case, monitoring the longitudinal changes in renal perfusion using serial Tc-99m-MAG3 renal scanning was beneficial for evaluating the pathophysiological background associated with the development of AKI. The potential impact of serial renal scanning in MCNS patients with AKI will also be discussed.
急性肾损伤（AKI）是微小病变型肾病综合征（MCNS）一种公认的并发症。既往报道支持与MCNS相关的AKI是可逆的这一观点；然而，关于MCNS中AKI的血流动力学基础的信息并不充分。我们在此描述一例患有MCNS的男性发生AKI的病例。在该病例中，使用连续的Tc-99m-MAG3肾扫描监测肾脏灌注的纵向变化，有助于评估与AKI发生相关的病理生理背景。还将讨论连续肾扫描对患有AKI的MCNS患者的潜在影响。
