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从益母草新鲜叶子中分离得到的两种新半日花烷型二萜及其在干燥过程中的降解产物

Two new labdane diterpenes from fresh leaves of Leonurus japonicus and their degradation during drying.

作者信息

Fuchino Hiroyuki, Daikonya Akihiro, Kumagai Takeo, Goda Yukihiro, Takahashi Yutaka, Kawahara Nobuo

机构信息

Research Center for Medicinal Plant Resources, National Institute of Biomedical Innovation, 1-2 Hachimandai, Tsukuba, Ibaraki 305-0843, Japan.

出版信息

Chem Pharm Bull (Tokyo). 2013;61(5):497-503. doi: 10.1248/cpb.c12-00670.

DOI:10.1248/cpb.c12-00670
PMID:23649192
Abstract

Degradation of the components of Leonurus Herb was examined during drying. Compounds 1 and 2 were detected on TLC at lower temperature, but not at higher temperature. Their chemical structures were determined by spectral methods. They immediately decomposed even at 40°C in chloroform solution. They are believed to be transformed through a retro-aldol reaction. Compounds 1 and 2 have not been previously reported.

摘要

在干燥过程中对益母草的成分降解情况进行了研究。化合物1和2在较低温度下可通过薄层色谱法检测到,但在较高温度下则检测不到。它们的化学结构通过光谱方法确定。即使在40°C的氯仿溶液中,它们也会立即分解。据信它们是通过逆羟醛反应转化的。化合物1和2此前未见报道。

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