Kim Yong Beom, Chang Young Jin, Jung Wol Seon, Byen Sang Ho, Jo Youn Yi
Department of Anesthesiology and Pain Medicine, Gachon University Gil Medical Center, 1198 Guwol-dong, Namdong-gu, Incheon, 405-760, Korea.
J Anesth. 2013 Dec;27(6):827-31. doi: 10.1007/s00540-013-1628-2. Epub 2013 May 7.
This prospective, randomized trial was designed to assess whether the i-gel supraglottic airway device is suitable for volume-controlled ventilation while applying positive end-expiratory pressure (PEEP) of 5 cmH(2)O under general anesthesia. It was believed that this device might improve arterial oxygenation.
Forty adult patients (aged 20-60 years) scheduled for elective orthopedic surgery were enrolled in this study. Twenty patients were ventilated without external PEEP [zero positive end-expiratory pressure (ZEEP) group], and the other 20 were ventilated with PEEP 5 cmH(2)O (PEEP group) after placing an i-gel device. Volume-controlled ventilation at a tidal volume (TV) of 8 ml/kg of ideal body weight, leak volume, and arterial blood gas analysis were investigated.
The incidences of a significant leak were similar in the ZEEP and PEEP groups (3/20 and 1/20, respectively; P = 0.605), as were leak volumes. No significant PaO(2) difference was observed between the two groups at 1 h after satisfactory i-gel insertion (215 ± 38 vs. 222 ± 54; P = 0.502).
The use of an i-gel during PEEP application at 5 cmH(2)O did not increase the incidence of a significant air leak, and a PEEP of 5 cmH(2)O failed to improve arterial oxygenation during controlled ventilation in healthy adult patients.
本前瞻性随机试验旨在评估i-gel声门上气道装置在全身麻醉下应用5 cmH₂O呼气末正压(PEEP)时是否适用于容量控制通气。据信该装置可能会改善动脉氧合。
40例计划行择期骨科手术的成年患者(年龄20 - 60岁)纳入本研究。20例患者在无外部PEEP情况下通气[零呼气末正压(ZEEP)组],另外20例在置入i-gel装置后以5 cmH₂O的PEEP进行通气(PEEP组)。研究了以理想体重8 ml/kg的潮气量(TV)进行容量控制通气、漏气量及动脉血气分析情况。
ZEEP组和PEEP组严重漏气的发生率相似(分别为3/20和1/20;P = 0.605),漏气量也相似。在成功置入i-gel 1小时后,两组之间未观察到显著的PaO₂差异(215 ± 38 vs. 222 ± 54;P = 0.502)。
在应用5 cmH₂O的PEEP期间使用i-gel并未增加严重漏气的发生率,且5 cmH₂O的PEEP未能改善健康成年患者控制通气期间的动脉氧合。