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大鼠肾上腺束状带和网状带对催产素治疗的反应。

The response of rat adrenal zona fasciculata and zona reticularis to oxytocin treatment.

作者信息

Plećas B, Hristić M, Jovović D, Popović A

机构信息

Department of Physiology, Faculty of Pharmacy, Belgrade/Yugoslavia.

出版信息

Exp Clin Endocrinol. 1990 Apr;95(2):192-6. doi: 10.1055/s-0029-1210951.

Abstract

The response of the adrenal zona fasciculata (ZF) and zona reticularis (ZR) to oxytocin (OT) was examined in male rats using a stereological method. The 10-day administration of 0.25 IU OT/100 g daily caused an enlargement of ZF due to cell hypertrophy associated with striking lipid accumulation. The volume of ZR was decreased, this change being the consequence of the reduced cell population. The possible site of OT action is discussed.

摘要

采用体视学方法研究了雄性大鼠肾上腺束状带(ZF)和网状带(ZR)对催产素(OT)的反应。每天给予0.25 IU OT/100 g,连续给药10天,导致束状带因细胞肥大并伴有显著脂质蓄积而增大。网状带体积减小,这种变化是细胞数量减少的结果。文中讨论了OT作用的可能部位。

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