Andreis P G, Tortorella C, Nussdorfer G G
Department of Anatomy, University of Padua, Italy.
Life Sci. 1993;53(17):1353-6. doi: 10.1016/0024-3205(93)90595-t.
Pancreatic polypeptide (PP) dose-dependently enhanced both basal and submaximally ACTH-stimulated corticosterone production by dispersed zona fasciculata/reticularis cells of the rat adrenal gland. Conversely PP did not affect either basal or ACTH- and angiotensin-II-stimulated aldosterone and corticosterone secretion of zona glomerulosa cells. These findings could throw light on the physiological significance of the marked increase in the pancreatic release of PP during stresses.