Department of Cardiology, The Heart Centre, Copenhagen University Hospital, Rigshospitalet, Copenhagen University, 2100 Copenhagen, Denmark.
Biomarkers. 2013 Jun;18(4):304-9. doi: 10.3109/1354750X.2013.776635. Epub 2013 May 7.
The aim was to assess serial measurements of high-sensitivity cardiac troponin T (hs-cTNT) post-exercise in patients with stable coronary artery disease (CAD).
Twelve patients with positive coronary angiograms (CAD positives) and 12 controls performed an exercise stress test.
CAD positive had higher baseline and peak concentrations of hs-cTNT than controls. Significant increases in hs-cTNT were seen in both groups after exercise. In two-third of patients the peak in hs-cTNT was above the 99th percentile.
hs-cTNT is higher in patients with stable coronary disease than in controls and exceeds the diagnostic cut-off value for myocardial infarction in a majority of patients with CAD after exercise.
评估稳定型冠状动脉疾病（CAD）患者运动后高敏心肌肌钙蛋白 T（hs-cTNT）的连续测量值。
12 例冠状动脉造影阳性（CAD 阳性）患者和 12 例对照者进行运动应激试验。
CAD 阳性者的 hs-cTNT 基线和峰值浓度均高于对照组。两组运动后 hs-cTNT 均显著升高。三分之二的患者 hs-cTNT 峰值超过第 99 百分位。
稳定型冠状动脉疾病患者的 hs-cTNT 高于对照组，且大多数 CAD 患者运动后 hs-cTNT 超过心肌梗死的诊断截断值。
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