Verity C M, Morgan H, Mott M, Oakhill A
Child Development Centre, Addenbrooke's Hospital, Cambridge.
Dev Med Child Neurol. 1990 Jun;32(6):481-92. doi: 10.1111/j.1469-8749.1990.tb16973.x.
Abnormal visual evoked potentials (VEPs) have been reported in children treated for acute lymphoblastic leukaemia (ALL), which suggests that VEPs may be useful in screening for toxicity. The authors investigated this by recording flash and pattern VEPs in a control group of 34 siblings of patients, a group of six children studied longitudinally during the early stages of treatment for ALL, and three other follow-up groups. In only three follow-up patients were VEP results outside the normal range and the six ALL patients did not develop new abnormalities during early treatment. Although differences were detected between the groups, there was no evidence of VEPs being a useful means of monitoring the treatment of individual patients.
据报道，接受急性淋巴细胞白血病（ALL）治疗的儿童存在异常视觉诱发电位（VEP），这表明VEP可能有助于毒性筛查。作者通过记录34名患者兄弟姐妹的对照组、一组在ALL治疗早期进行纵向研究的6名儿童以及其他三个随访组的闪光和图形VEP对此进行了研究。只有三名随访患者的VEP结果超出正常范围，六名ALL患者在早期治疗期间未出现新的异常。尽管在组间检测到差异，但没有证据表明VEP是监测个体患者治疗的有用手段。
