Department of Neurosciences, Catholic University, Rome, Italy.
Eur Neurol. 2013;70(1-2):10-5. doi: 10.1159/000348717. Epub 2013 May 3.
In this prospective study, we used one diagnostic protocol to establish an early diagnosis in patients with ocular palsies in absence of other neurological findings.
The study was performed on a consecutive series of 132 patients who visited our Neurological Department for ptosis and/or diplopia in absence of other neurological signs, using the same diagnostic protocol.
An etiological diagnosis was made in 74% of cases during a mean time of 17 ± 23 months from symptom onset. Myasthenia gravis was the most common diagnosis (n = 60, 45.5%). Thirty-four cases (26%) remained undiagnosed in spite of a follow-up lasting 32 ± 33 months on average.
Identifying the cause of an isolated ocular palsy can be difficult, and an extended follow-up time does not aid in further establishment of the diagnosis.
在这项前瞻性研究中，我们使用一种诊断方案在没有其他神经学发现的情况下对眼肌麻痹患者进行早期诊断。
我们对连续就诊于神经内科的 132 例因眼睑下垂和/或复视而无其他神经学体征的患者进行了研究，使用相同的诊断方案。
在症状出现后 17±23 个月的平均时间内，74%的患者确定了病因诊断。肌无力是最常见的诊断（n=60，45.5%）。尽管平均随访时间为 32±33 个月，但仍有 34 例（26%）未确诊。
确定孤立性眼肌麻痹的病因可能很困难，延长随访时间并不能有助于进一步确定诊断。
