Woolery-Lloyd Heather C, Keri Jonette, Doig Stefan
Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, Miami, FL, USA.
J Drugs Dermatol. 2013 Apr;12(4):434-7.
In this review, we examine published data reporting the efficacy of pharmaceutical agents to treat associated postinflammatory hyperpigmentation commonly seen in skin of color. Retinoids and azelaic acid have been widely used to treat acne. Now there are increasing data describing their use in skin of color for the treatment of both acne and the subsequent postinflammatory hyperpigmentation. Historically, some dermatologists have been hesitant to use retinoids in skin of color because of perceived hypersensitivity in this patient population. However, recent data support the use of retinoids and azelaic acid in skin of color as both safe and beneficial.
在本综述中,我们研究了已发表的数据,这些数据报告了药物治疗常见于有色人种皮肤的相关炎症后色素沉着的疗效。维甲酸和壬二酸已被广泛用于治疗痤疮。现在,越来越多的数据描述了它们在有色人种皮肤中用于治疗痤疮及随后的炎症后色素沉着的情况。从历史上看,一些皮肤科医生一直不愿在有色人种皮肤中使用维甲酸,因为认为该患者群体存在超敏反应。然而,最近的数据支持在有色人种皮肤中使用维甲酸和壬二酸,因为它们既安全又有益。