Dréno Brigitte, Araviiskaia Elena, Kerob Delphine, Andriessen Anneke, Anfilova Maryna, Arenbergerova Monika, Forero Barrios Olga L, Bukvić Mokos Zrinka, Haedersdal Merete, Hofmann Maja A, Khamaysi Ziad, Kosmadaki Marita, Lesiak Aleksandra, Roó Elia, Zbranca-Toporas Anca, Wiseman Marni C, Zimmo Sameer, Guerin Lucie, Fabbrocini Gabriella
Cell Therapy and Gene Therapy Unit, Department of Dermato-Oncology, The Faculty of Medicine, University of Nantes, Nantes, France.
Department of Dermatology & Venereology, First Pavlov State Medical University of Saint Petersburg, Saint Petersburg, Russia.
J Cosmet Dermatol. 2020 Sep;19(9):2201-2211. doi: 10.1111/jocd.13497. Epub 2020 Jun 17.
Acne vulgaris (acne), a common inflammatory skin disorder, has its peak incidence between 14 and 19 years of age, with girls frequently developing acne earlier than boys. Over recent years, persistent acne is becoming more prevalent in adult women.
This review and panel discussion addresses challenges in acne management, particularly in adult women. The role which nonprescription acne treatment can play is explored when used as monotherapy or as an adjunctive treatment for acne of all severity.
The best available evidence on nonprescription acne treatment was coupled with the opinion of an international expert panel of dermatologists to adopt statements and recommendations discussed in this review.
All severity of acne has a significant burden on patients. Addressing environmental factors that are important for the individual with acne may help to educate, prevent, effectively manage, and maintain acne, as per the panel. They agreed that the adult female acne population has unique needs because of their aging skin and social environment. Nonprescription acne treatment products may help to balance the efficacy and tolerability of prescription acne treatment. Currently, there are no specific guidelines for how to use nonprescription acne treatment products in these patients.
The panel agreed that guidelines including nonprescription acne treatment either as monotherapy for mild acne or in combination with prescription treatments for more severe acne would address a significant unmet need.
寻常痤疮是一种常见的炎症性皮肤病，发病高峰期在14至19岁之间，女孩通常比男孩更早出现痤疮。近年来，持续性痤疮在成年女性中越来越普遍。
本综述和专家小组讨论探讨了痤疮管理中的挑战，特别是在成年女性中。探讨了非处方痤疮治疗作为单一疗法或作为各种严重程度痤疮的辅助治疗时所能发挥的作用。
将关于非处方痤疮治疗的最佳现有证据与国际皮肤科专家小组的意见相结合，以采纳本综述中讨论的声明和建议。
所有严重程度的痤疮对患者都有很大负担。根据专家小组的意见，解决对痤疮患者重要的环境因素可能有助于教育、预防、有效管理和维持痤疮。他们一致认为，成年女性痤疮患者群体由于其皮肤老化和社会环境而有独特的需求。非处方痤疮治疗产品可能有助于平衡处方痤疮治疗的疗效和耐受性。目前，对于如何在这些患者中使用非处方痤疮治疗产品尚无具体指南。
专家小组一致认为，将非处方痤疮治疗作为轻度痤疮的单一疗法或与更严重痤疮的处方治疗联合使用的指南将满足一项重大的未满足需求。
