Infectious Diseases Unit, The Royal Children's Hospital Melbourne, Parkville, Australia.
Adv Exp Med Biol. 2013;764:13-26. doi: 10.1007/978-1-4614-4726-9_2.
Non-typhoidal Salmonellae (NTS) are an important cause of infectious diarrhoea world-wide. In the absence of immune deficiency, gastroenteritis caused by NTS is usually mild, self limiting and rarely requires intervention. NTS are also an important cause of invasive disease, particularly in developing countries, likely secondary to the high prevalence of coexisting malnutrition, malaria and HIV infection. This review provides an overview of the microbiology, epidemiology and pathogenesis of NTS, and compares recommendations for the treatment of NTS gastroenteritis in children.
非伤寒沙门氏菌(NTS)是全球范围内引起感染性腹泻的重要原因。在没有免疫缺陷的情况下,NTS 引起的胃肠炎通常较轻,具有自限性,很少需要干预。NTS 也是侵袭性疾病的重要原因,特别是在发展中国家,这可能与共存的营养不良、疟疾和 HIV 感染的高患病率有关。本文综述了 NTS 的微生物学、流行病学和发病机制,并比较了儿童 NTS 胃肠炎治疗的推荐意见。